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Medical Science Monitor Basic Research


eISSN: 1643-3750

Effects of Use of a Continuous Positive Airway Pressure Device on Glaucoma

Seckin Ulusoy, Meltem Erden, Mehmet Emre Dinc, Nurdogan Yavuz, Erdem Caglar, Abdullah Dalgic, Coskun Erdogan

ENT Clinics, TR Ministry of Health, Gaziosmanpasa Taksim Training and Research Hospital, Istanbul, Turkey

Med Sci Monit 2015; 21:3415-3419

DOI: 10.12659/MSM.895897

Available online: 2015-11-08

Published: 2015-11-08


BACKGROUND: The aim of this study was to investigate the prevalence of glaucoma in obstructive sleep apnea syndrome (OSAS) and to determine the efficacy of the equipment used in the treatment of this disease.
MATERIAL AND METHODS: In this cross-sectional study, 38 patients with OSAS used the continuous positive airway pressure (CPAP) device (Group 1) and 32 patients with OSAS refused CPAP device (Group 2). Thirty-six patients did not have OSAS (Group 3).
RESULTS: Patient age, gender, height, weight, and neck circumference did not differ among groups (p>0.05); and the apnea-hypopnea index (AHI) and respiratory disturbance index (RDI) values did not differ between Groups 1 and 2 (p>0.05). Vision and pachymetric values did not differ among groups (p>0.05). The IOP was significantly higher in Group 2 than in Group 1 (p<0.05) but did not differ between Groups 1 and 3 (p>0.05). The fundus C/D ratio was significantly higher (p<0.05) in Group 2 than in the other groups but did not differ between Groups 1 and 3 (p>0.05). In Group 1, 2, and 3, 5.2%, 12.5%, and 0%, respectively, of patients had glaucoma.
CONCLUSIONS: OSAS should be considered a significant risk factor for glaucoma. Eye tests may help to identify individuals with undiagnosed OSAS, and such testing of patients with diagnosed OSAS may allow early detection of glaucoma and referral of such patients for CPAP therapy to prevent development of complications.

Keywords: Continuous Positive Airway Pressure - methods, Adult, Cross-Sectional Studies, Fundus Oculi, Glaucoma - therapy, Polysomnography, Respiration, Sleep Apnea, Obstructive - therapy, Vision, Ocular