Logo MSM

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo MSM Logo MSM Logo MSM

07 December 2015 : Clinical Research

Comparison of 3 ABR Methods for Diagnosis of Retrocochlear Hearing Impairment

Krzysztof M. KochanekADF, Lech ŚliwaCDEF, Marek GołębiowskiD, Adam PiłkaBC, Henryk SkarżyńskiG

DOI: 10.12659/MSM.895291

Med Sci Monit 2015; 21:3814-3824

Abstract

BACKGROUND: The purpose of this study was to compare the effectiveness of methods for screening for retrocochlear pathologies based on auditory evoked brainstem responses (ABRs). The study compared the sensitivity, specificity, and effectiveness of these 3 techniques.

MATERIAL AND METHODS: The methods were: (i) standard ABR utilizing click-evoked responses, (ii) stacked ABR based on derived-band responses, and (iii) ABRs evoked by tone-pips (ABR TP). The methods were tested on patients with retrocochlear pathologies confirmed by MRI-Gd, normal-hearing subjects, and patients with cochlear hearing loss. The system and software used in the tests was NavPro AEP v.6.2.0 (BioLogic – Natus). Prior to testing, all subjects were given comprehensive audiologic and otologic examinations, including MR imaging. Sensitivity and specificity functions and predictive values of methods were determined.

RESULTS: The stacked ABR method as realized in the NavPro system exhibited high sensitivity but specificity was very low, due to the high variability of stacked ABR amplitudes. The standard ABR method had good specificity, but low sensitivity in cases of small tumors (below 1 cm in diameter). Best sensitivity and specificity was obtained with the ABR TP method.

CONCLUSIONS: The stacked ABR method allows small acoustic tumors to be detected, but produces high percentage of false positive results. The ABR TP method offers good sensitivity and specificity, and relatively high predictive value. The best option would be to use a two-stage screening, consisting of a standard ABR in the first stage and an ABR TP test in the second.

Keywords: Hearing Disorders - diagnosis, Cochlea - physiopathology, Sensitivity and Specificity

0 Comments

Weekly Editorial

27 September 2021 : Editorial

Editorial: Global Regulatory Initiatives Deliver Accelerated Approval of the First Bispecific Therapeutic Monoclonal Antibody for Advanced Non-Small Cell Lung Cancer (NSCLC)

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.934854

Med Sci Monit 2021; 27:e934854

SARS-CoV-2/COVID-19

08 September 2021 : Clinical Research

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

Med Sci Monit In Press; DOI: 10.12659/MSM.932788  

16 July 2021 : Review article

Silent Hypoxemia in Patients with COVID-19 Pneumonia: A Review

Med Sci Monit In Press; DOI: 10.12659/MSM.930776  

09 July 2021 : Database Analysis

A Simple Clinical Prediction Tool for COVID-19 in Primary Care with Epidemiology: Temperature-Leukocytes-CT...

Med Sci Monit In Press; DOI: 10.12659/MSM.931467  

In Press

24 Sep 2021 : Clinical Research

A Single-Center Study of a Resin Inlay Dental Implant-Fixed Prosthesis for Closing Proximal Contact Loss in...

Med Sci Monit In Press; DOI: 10.12659/MSM.933809  

24 Sep 2021 : Database Analysis

Relationships Between Obstructive Sleep Apnea and Cardiovascular Disease: A Bibliometric Analysis (2010-2021)

Med Sci Monit In Press; DOI: 10.12659/MSM.933448  

24 Sep 2021 : Database Analysis

A Statistical Prediction Model for Survival After Kidney Transplantation from Deceased Donors

Med Sci Monit In Press; DOI: 10.12659/MSM.933559  

24 Sep 2021 : Clinical Research

Value of Ocular Endoscopy in Extraction of Intraocular Foreign Bodies of Cilia in Patients with Open Ocular...

Med Sci Monit In Press; DOI: 10.12659/MSM.932970  

Most Viewed Current Articles

20 Mar 2020 : Clinical Research

Social Capital and Sleep Quality in Individuals Who Self-Isolated for 14 Days During the Coronavirus Diseas...

DOI :10.12659/MSM.923921

Med Sci Monit 2020; 26:e923921

15 Apr 2020 : Clinical Research

Psychological Impact and Coping Strategies of Frontline Medical Staff in Hunan Between January and March 20...

DOI :10.12659/MSM.924171

Med Sci Monit 2020; 26:e924171

05 May 2020 : Review article

An Evidence Based Perspective on mRNA-SARS-CoV-2 Vaccine Development

DOI :10.12659/MSM.924700

Med Sci Monit 2020; 26:e924700

26 Apr 2020 : Clinical Research

Comparison of Prevalence and Associated Factors of Anxiety and Depression Among People Affected by versus P...

DOI :10.12659/MSM.924609

Med Sci Monit 2020; 26:e924609

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750