Logo MSM

09 January 2015 : Original article

Association of Depression and Loneliness with Specific Cognitive Performance in Non-Demented Elderly Males

Ruu-Fen TzangDE, Albert C. YangCD, Heng-Liang YehB, Mu-En LiuD, Shih-Jen TsaiABCD

Med Sci Monit 2015; 21:100-104

Abstract

BACKGROUND: Loneliness and depression are very common in the aged population. Both have negative impacts on cognition in the elderly. The present study aimed to investigate the effect of loneliness and depression on total as well as specific cognitive domains in cognitively normal male subjects.

MATERIAL AND METHODS: A total of 189 cognitively normal male subjects were recruited and underwent Cognitive Abilities Screening Instrument (CASI) and Wechsler Digit Span Task tests. Depression was assessed by the Geriatric Depression Scale-Short Form (GDS-SF) and loneliness by UCLA loneliness scales. Partial correlation test was used to explore the correlation between loneliness/depression and total as well as specific cognition function, with the controlled factors of age and education.

RESULTS: Both depression and loneliness are negatively correlated with global cognitive function as evaluated with CASI (r=–0.227, p=0.002; r=–0.214, p=0.003, respectively). The domains of Attention, Orientation, Abstraction and judgment, and List-generating fluency of cognitive function were specifically associated with loneliness, and the domain of orientation was associated with depression after controlling the factors age and years of education.

CONCLUSIONS: Our findings suggest that loneliness and depression may have negative impacts on global and specific domains of cognitive function in non-demented elderly males. Both loneliness and depression should be actively recognized earlier and appropriately treated because they are significant sources of cognitive impairment in the elderly.

Keywords: Aged, 80 and over, Aging, Cognition - physiology, Cognition Disorders - complications, Depression - complications, Loneliness, Neuropsychological Tests, Psychometrics, Questionnaires, Taiwan

0 Comments

This Week Editorial

02 August 2021 : Editorial

Editorial: The National COVID Cohort Collaborative Consortium Combines Population Data with Machine Learning to Evaluate and Predict Risk Factors for the Severity of COVID-19

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.934171

Med Sci Monit 2021; 27:e934171

Coronavirus/Covid 19

30 July 2021 : Clinical Research

Rural and Female Patients with Old Myocardial Infarction Lacked Knowledge and Preventive Measures During th...

Med Sci Monit In Press  ::  DOI: 10.12659/MSM.928512  

16 July 2021 : Review article

Silent Hypoxemia in Patients with COVID-19 Pneumonia: A Review

Med Sci Monit In Press  ::  DOI: 10.12659/MSM.930776  

09 July 2021 : Database Analysis

A Simple Clinical Prediction Tool for COVID-19 in Primary Care with Epidemiology: Temperature-Leukocytes-CT...

Med Sci Monit In Press  ::  DOI: 10.12659/MSM.931467  

07 July 2021 : Database Analysis

Chest Radiological Findings and Clinical Characteristics of Laboratory-Confirmed COVID-19 Patients from Sau...

Med Sci Monit In Press  ::  DOI: 10.12659/MSM.932441  

In Press

03 Aug 2021 : Clinical Research

Comparison of Outcomes Following TiRobot-Assisted Sacroiliac Screw Fixation with Bone Grafting and Traditio...

Med Sci Monit In Press  ::  DOI: 10.12659/MSM.932724  

02 Aug 2021 : Database Analysis

RNA N6-Methyladenosine Patterns in Hepatocellular Carcinoma Reveal a Distinct Immune Infiltration Landscape...

Med Sci Monit In Press  ::  DOI: 10.12659/MSM.930994  

02 Aug 2021 : Clinical Research

Vitamin D Receptor Is a Sepsis-Susceptibility Gene in Chinese Children

Med Sci Monit In Press  ::  DOI: 10.12659/MSM.932518  

30 Jul 2021 : Clinical Research

Rural and Female Patients with Old Myocardial Infarction Lacked Knowledge and Preventive Measures During th...

Med Sci Monit In Press  ::  DOI: 10.12659/MSM.928512  

Most Viewed

20 Mar 2020 : Clinical Research

Social Capital and Sleep Quality in Individuals Who Self-Isolated for 14 Days During the Coronavirus Diseas...

DOI :10.12659/MSM.923921

Med Sci Monit 2020; 26:e923921

15 Apr 2020 : Clinical Research

Psychological Impact and Coping Strategies of Frontline Medical Staff in Hunan Between January and March 20...

DOI :10.12659/MSM.924171

Med Sci Monit 2020; 26:e924171

05 May 2020 : Review article

An Evidence Based Perspective on mRNA-SARS-CoV-2 Vaccine Development

DOI :10.12659/MSM.924700

Med Sci Monit 2020; 26:e924700

26 Apr 2020 : Clinical Research

Comparison of Prevalence and Associated Factors of Anxiety and Depression Among People Affected by versus P...

DOI :10.12659/MSM.924609

Med Sci Monit 2020; 26:e924609

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750