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Medical Science Monitor Basic Research


eISSN: 1643-3750

Spectral Optical Coherence Tomography vs. fluorescein pattern for rigid gas-permeable lens fit

Ilona Piotrowiak, Bartłomiej Jan Kaluzny, Beata Danek, Adam Chwiędacz, Bartosz Łukasz Sikorski, Grażyna Malukiewicz

Department of Ophthalmology, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland

Med Sci Monit 2014; 20:1137-1141

DOI: 10.12659/MSM.890269

Available online: 2014-07-04

Published: 2014-07-04


Background: This study aimed to evaluate anterior segment spectral optical coherence tomography (AS SOCT) for assessing the lens-to-cornea fit of rigid gas-permeable (RGP) lenses. The results were verified with the fluorescein pattern method, considered the criterion standard for RGP lens alignment evaluations.
Material and Methods: Twenty-six eyes of 14 patients were enrolled in the study. Initial base curve radius (BCR) of each RGP lens was determined on the basis of keratometry readings. The fluorescein pattern and AS SOCT tomograms were evaluated, starting with an alignment fit, and subsequently, with BCR reductions in increments of 0.1 mm, up to 3 consecutive changes. AS SOCT examination was performed with the use of RTVue (Optovue, California, USA).
Results: The average BCR for alignment fits, defined according to the fluorescein pattern, was 7.8 mm (SD=0.26). Repeatability of the measurements was 18.2%. BCR reductions of 0.1, 0.2, and 0.3 mm resulted in average apical clearances detected with AS SOCT of 12.38 (SD=9.91, p<0.05), 28.79 (SD=15.39, p<0.05), and 33.25 (SD=10.60, p>0.05), respectively.
Conclusions: BCR steepening of 0.1 mm or more led to measurable changes in lens-to-cornea fits. Although AS SOCT represents a new method of assessing lens-to-cornea fit, apical clearance detection with current commercial technology showed lower sensitivity than the fluorescein pattern assessment.

Keywords: Anterior Eye Segment - anatomy & histology, Adult, Contact Lenses, Fluorescein - metabolism, Gases - metabolism, Permeability, Tomography, Optical Coherence - methods, young adult