Scimago Lab
powered by Scopus
call: +1.631.470.9640
Mon-Fri 10 am - 2 pm EST


Medical Science Monitor Basic Research


eISSN: 1643-3750

Utility of computed tomography in assessment of pulmonary hypertension secondary to biomass smoke exposure

Bunyamin Sertogullarindan, Aydin Bora, Alpaslan Yavuz, Selami Ekin, Hulya Gunbatar, Ahmet Arisoy, Serhat Avcu, Bulent Ozbay

Department of Chest Disorders, Yuzuncu Yil University School of Medical Science, Van, Turkey

Med Sci Monit 2014; 20:368-373

DOI: 10.12659/MSM.890174

Available online: 2014-03-05

Published: 2014-03-05


Background: The aim of this study was to investigate the feasibility of main pulmonary artery diameter quantification by thoracic computerized tomography (CT) in the diagnosis of pulmonary hypertension seconder to biomass smoke exposure.
Material and Methods: One hundred and four women subjects with biomass smoke exposure and 20 healthy women subjects were enrolled in the prospective study. The correlation between echocardiographic estimation of systolic pulmonary artery pressure and the main pulmonary artery diameter of the cases were studied.
Results: The main pulmonary artery diameter was 26.9±5.1 in the control subjects and 37.1±6.4 in subjects with biomass smoke exposure. This difference was statistically significant (p<0.001). The systolic pulmonary artery pressure was 22.7±12.4 in the control subjects and 57.3±22 in subjects with biomass smoke exposure. This difference was statistically significant (p<0.001). Systolic pulmonary artery pressure was significantly correlated with the main pulmonary artery diameter (r=0.614, p<0.01). A receiver operating characteristic (ROC) curve analysis showed that a value of 29 mm of the main pulmonary artery diameter differentiated between pulmonary hypertension and non-pulmonary hypertension patients. The sensitivity of the measurement to diagnose pulmonary hypertension was 91% and specificity was 80%.
Conclusions: Our results indicate that main pulmonary artery diameter measurements by SCT may suggest presence of pulmonary hypertension in biomass smoke exposed women.

Keywords: Biomass, Hypertension, Pulmonary, Blood Pressure, Environmental Exposure - analysis, Hypertension, Pulmonary - radiography, Pulmonary Artery - radiography, ROC Curve, Smoke - adverse effects, Systole, Tomography, X-Ray Computed - utilization