31 January 2014 : Hypothesis
Lanthanum-containing hydroxyapatite coating on ultrafine-grained titanium by micro-arc oxidation: A promising strategy to enhance overall performance of titaniumZhennan DengADEF, Lili WangBF, Dafeng ZhangCF, Jinsong LiuCF, Chuantong LiuCF, Jianfeng MaAG
Med Sci Monit 2014; 20:163-166
ABSTRACT: Titanium is widely used in biomedical materials, particularly in dental implants, because of its excellent biocompatibility and mechanical characteristics. However, titanium implant failures still remain in some cases, varying with implantation sites and patients. Improving its overall performance is a major focus of dental implant research. Equal-channel angular pressing (ECAP) can result in ultrafine-grained titanium with superior mechanical properties and better biocompatibility, which significantly benefits dental implants, and without any harmful alloying elements. Lanthanum (La) can inhibit the acidogenicity of dental plaque and La-containing hydroxyapatite (La-HA) possesses a series of attractive properties, in contrast to La-free HA. Micro-arc oxidation (MAO) is a promising technology that can produce porous and firmly adherent hydroxyapatite (HA) coatings on titanium substrates. Therefore, we hypothesize that porous La-containing hydroxyapatite coatings with different La content (0.89%, 1.3% and 1.79%) can be prepared on ultrafine-grained (~200–400 nm) titanium by ECAP and MAO in electrolytic solution containing 0.2 mol/L calcium acetate, 0.02 mol/L beta-glycerol phosphate disodium salt pentahydrate (beta-GP), and lanthanum nitrate with different concentrations to further improve the overall performance of titanium, which are expected to have great potential in medical applications as a dental implant.
Keywords: Dental Implants, Biocompatible Materials - chemistry, Durapatite - chemistry, Lanthanum - chemistry, Materials Testing, Oxidation-Reduction, Porosity, Surface Properties, Titanium - therapeutic use
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