28 December 2010
Acute myopia and angle closure glaucoma associated with topiramate use: A case series
AliReza Dehghani, Leila Rezaei, AliReza PeymanDOI: 10.12659/AJCR.881366
Am J Case Rep 2010; 11:241-243
Abstract
Abstract
Background: To report 7 cases of topiramate-induced angle closure glaucoma.
Case Report: We present 7 cases of angle closure glaucoma after topiramate administration for neuropsychological disorders. All patients were female. The average age of patients was 33.28 years (ranging from 19 to 44 years). The mean interval between drug administration and symptoms onset was 12.2 days (ranging from 4 to 30 days).The mean best corrected visual acuity was 3 meters counting fingers in both eyes. The mean refractive errors was –6.50 diopters (ranging from –3.00 to –12.00 diopters). The mean intraocular pressure was 44.71 mmHg (ranging from 34 to 60 mmHg). The mean normalization time of intraocular pressure was 12.30 hours (ranging from 8 to 23 hours).
Conclusions: Acute myopia and acute angle closure glaucoma are serious adverse effects of topiramate use, both of which are reversible with immediate discontinuation of the drug. Thus, obtaining the drug history of the patients is critical in evaluation of angle closure glaucoma.
Keywords: Topiramat, angle closure, Glaucoma
In Press
12 Feb 2024 : Case report
Erdheim-Chester Disease Occult on Radiographs and CT but Visible on MRI and PETAm J Case Rep In Press; DOI: 10.12659/AJCR.941169
12 Feb 2024 : Case report
Surgical Treatment of Spontaneous Superficial Temporal Artery Arteriovenous Malformation: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.942839
13 Feb 2024 : Case report
Warfarin Woes: A Rare Case of Hemoperitoneum with Intramural Small Bowel HematomaAm J Case Rep In Press; DOI: 10.12659/AJCR.943519
13 Feb 2024 : Case report
Hemorrhagic Presentation in Primary Central Nervous System Lymphoma: A Case StudyAm J Case Rep In Press; DOI: 10.12659/AJCR.942951
Most Viewed Current Articles
07 Mar 2024 : Case report
Neurocysticercosis Presenting as Migraine in the United StatesDOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
23 Feb 2022 : Case report
Penile Necrosis Associated with Local Intravenous Injection of CocaineDOI :10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250