Preoperative prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization in patients undergoing intranasal surgery
Brian D. Nicholas, Geeta Bhargave, Ayse Hatipoglu, Ryan Heffelfinger, Marc Rosen, Edmund A. Pribitkin
Med Sci Monit 2010; 16(8): CR365-368
Available online: 2010-08-01
Background: The goal of this study was to determine the rates of carriage of methicillin-resistant Staphylococcus aureus among patients undergoing intranasal surgery.
Material/Methods: One hundred and sixty five patients undergoing inpatient and outpatient rhinologic surgery over a six-month period were enrolled in the study. Patients completed a short questionnaire prior to surgery. Culture swabs of the anterior nares and nasal vestibule were sent to the microbiology lab for evaluation for methicillin-resistant Staphylococcus aureus. Cultures were grown on a MRSA-specific agar plate and were considered final after 48 hours of incubation. The primary endpoint was a positive MRSA culture.
Results: Of the one hundred fifty seven patients with nasal cultures taken, two had positive cultures for methicillin-resistant Staphylococcus aureus. Of those with positive cultures, both had a history of prior infection with methicillin-resistant Staphylococcus aureus.
Conclusions: While antibiotic usage among the study group is far higher than the national average, the rates of nasal carriage of methicillin-resistant Staphylococcus aureus mirrors that described in other studies for the general population. The authors conclude that methicillin-resistant Staphylococcus aureus does not represent a significant source of infection among those undergoing intranasal surgery.
Keywords: Middle Aged, Nasal Cavity - surgery, Methicillin-Resistant Staphylococcus aureus - growth & development, Male, Humans, Female, Colony Count, Microbial, Child, Aged, 80 and over, Aged, Adult, Adolescent, Abscess - pathology, Preoperative Care, Prevalence, Staphylococcal Infections - microbiology