29 August 2008
Molecular study of methicillin-resistant Staphylococcus aureus isolates at a neonatal high-risk unit in Merida, VenezuelaElsa VelazcoABCDEFG, Beatriz NievesAE, Ana VindelDF, Evelyn AlviarezBF, Betty GutierrezB, Guillermo BianchiC
Med Sci Monit 2008; 14(9): PI25-31 :: ID: 867945
Methicillin-resistant Staphylococcus aureus (MRSA) is a multiresistant microorganisms which holds first place in the world as a nosocomial pathogen. Special attention has therefore been directed to specific nosocomial surveillance systems and strict infection control measures for this microorganism in which the microbiological laboratory plays an important role by applying phenotypic and genotypic methods that permit establishing their epidemiological relationship especially in hospital outbreaks. In the present study the general objective was to study MRSA strains isolated from neonates with nosocomial infections and from healthcare personnel working in the Neonatal High Risk Unit (NHRU) of the Andes University Hospital Autonomous Institute (AUHAI) in Mérida, Venezuela.
Material and Method
Forty-three S. aureus isolates were analyzed by phenotypic and genotypic methods.
In these strains, antibiotypes resistant to oxacillin, gentamicin, erythromycin, and tobramycin predominated (50%). The greater percentage of MRSA strains isolated from health personnel as well as two neonates were described as pulse types Ia and Ib, belonging to phage group II, containing type IV SCCmecA and resistant to macrolides and aminoglycosides and sensitive to clindamycin and trimethoprim-sulfamethoxazole.
This is the first reported case of SCCmecA type IV MRSA found in the NHRU of the AUHAI.
Keywords: Methicillin Resistance, Staphylococcal Infections - prevention & control, Intensive Care Units, Neonatal, Methicillin - therapeutic use, Infectious Disease Transmission, Professional-to-Patient, Infection Control - methods, Infant, Newborn, Venezuela - epidemiology, Staphylococcus aureus - metabolism, Cross Infection - microbiology, Anti-Bacterial Agents - therapeutic use
01 December 2021 : EditorialEditorial: SARS-CoV-2 Vaccine Responses and Breakthrough COVID-19
Med Sci Monit 2021; 27:e935624
03 December 2021 : Laboratory ResearchInfluenza and Influenza-Like Respiratory Virus Infections in Children During the 2019/20 Influenza Season a...
Med Sci Monit In Press; DOI: 10.12659/MSM.934862
08 November 2021 : Database AnalysisVirtual Screening and Molecular Docking to Study the Mechanism of Chinese Medicines in the Treatment of Cor...
Med Sci Monit In Press; DOI: 10.12659/MSM.934102
01 November 2021 : EditorialEditorial: What Can be Learned from National and International Vaccine Adverse Event Reporting Systems Duri...
Med Sci Monit 2022; 28:e935299
06 Dec 2021 : Animal ResearchAstragalus Flavone Induces Proliferation and Differentiation of Neural Stem Cells in a Cerebral Infarction ...
Med Sci Monit In Press; DOI: 10.12659/MSM.933830
06 Dec 2021 : Clinical ResearchAlteration of Serum Metabolites in Women of Reproductive Age with Chronic Constipation
Med Sci Monit In Press; DOI: 10.12659/MSM.934117
06 Dec 2021 : Clinical ResearchBody Composition Changes and Related Factors in Patients with Ulcerative Colitis: A Retrospective Single-Ce...
Med Sci Monit In Press; DOI: 10.12659/MSM.933942
Most Viewed Current Articles
20 Mar 2020 : Clinical ResearchSocial Capital and Sleep Quality in Individuals Who Self-Isolated for 14 Days During the Coronavirus Diseas...
Med Sci Monit 2020; 26:e923921
15 Apr 2020 : Clinical ResearchPsychological Impact and Coping Strategies of Frontline Medical Staff in Hunan Between January and March 20...
Med Sci Monit 2020; 26:e924171
05 May 2020 : Review articleAn Evidence Based Perspective on mRNA-SARS-CoV-2 Vaccine Development
Med Sci Monit 2020; 26:e924700