01 July 2008
The effect of chronic periodontitis on the development of atherosclerosis: review of the literature
Iwona Niedzielska, Tomasz Janic, Szymon Cierpka, Elzbieta SwietochowskaMed Sci Monit 2008; 14(7): RA103-106 :: ID: 863657
Abstract
Although research has demonstrated that odontogenic foci of infection can be dangerous to the function of other organs, a direct relationship between orofacial infections and systemic health has not been proved. Recently, bacterial and viral organisms involved in chronic inflammatory processes have also been regarded as risk factors for atherosclerosis. Periodontitis is one of the most common chronic bacterial infections. One of the first researchers to indicate a relationship between orofacial infections and atherosclerosis were Mattila et al. In 1989 they published a paper which identified periodontal disease as an independent predictor of the risk of myocardial infarction. For over ten years several authors have discussed the correlation between oral infections, and periodontal disease in particular, and the occurrence of coronary heart disease, myocardial infarction, and ischemic stroke. A review of the knowledge of the effects of periodontal disease on the development of atheromatous plaque is presented here. No scientific evidence was found to prove a direct association between odontogenic infections and atherosclerosis. However, such a relationship is probable in the light of the reviewed articles. Reliable markers should be sought which could accurately indicate the effect of periodontal disease on the condition of the arteries.
Keywords: Periodontitis - complications, Chronic Disease, Atherosclerosis - pathology
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
15 Apr 2024 : Laboratory Research
The Role of Copper-Induced M2 Macrophage Polarization in Protecting Cartilage Matrix in OsteoarthritisMed Sci Monit In Press; DOI: 10.12659/MSM.943738
07 Mar 2024 : Clinical Research
Knowledge of and Attitudes Toward Clinical Trials: A Questionnaire-Based Study of 179 Male Third- and Fourt...Med Sci Monit In Press; DOI: 10.12659/MSM.943468
08 Mar 2024 : Animal Research
Modification of Experimental Model of Necrotizing Enterocolitis (NEC) in Rat Pups by Single Exposure to Hyp...Med Sci Monit In Press; DOI: 10.12659/MSM.943443
18 Apr 2024 : Clinical Research
Comparative Analysis of Open and Closed Sphincterotomy for the Treatment of Chronic Anal Fissure: Safety an...Med Sci Monit In Press; DOI: 10.12659/MSM.944127
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952