Suriya Jayawardena, Jacob Eisdorfer, Elena Volozhanina, Muhammad Zarkaria
Med Sci Monit 2008; 14(7): CS55-59
Available online: 2008-07-01
Non-Hodgkin's Lymphoma is a heterogeneous group of lymphoproliferative malignancies which can have differing patterns of behavior and clinical presentation. Unlike Hodgkin's disease, Non-Hodgkin's Lymphoma is much less predictable and has a far greater predilection for disseminating to extranodal sites.
Material and Method: We offer a case of a 50 year old Caucasian male who presented with chest pain, and was ultimately diagnosed with follicular lymphoma by means of liver biopsy, in conjunction with immunohistochemistry. This malignancy grew at a rapid rate and over came our patient in a short period of time. The combination of a large tumor burden and cardiac infiltration made resuscitation extremely difficult when it became necessary, and this also made a positive outcome unlikely.
Conclusions: It is rare for an immunocompetent patient to present with cardiac lymphoma without any previous signs and symptoms. Due to the rarity and the vague clinical presentation there must be a high degree of suspicion in order to diagnose cardiac lymphoma. As evidenced by this case time is of the essence to increase the likelyhood of survival in these patients.
Keywords: Liver - radiography, Lymphoma, Non-Hodgkin - complications, Myocardium - pathology, Fatal Outcome, Chest Pain - complications