01 January 1998
Circadian changes in morphometric parameters of terminal placental villi and in the activity of syncytiotrophoblastic succinate dehydrogenase
Ewa Wielgus, Marcin Kamiński, Urszula Górkiewicz, Krzysztof Pawlicki, Stanisław Włoch, Jan TomalaMed Sci Monit 1998; 4(1): BR47-52 :: ID: 502824
Abstract
The study attempted to correlate to several anatomic and biochemical parameters of the human placenta. The area and diameter of terminal villi, and the area and height of the syncytiotrophoblast were assessed. The trophoblastic activity of succinate dehydrogenase, an enzyme conditioning the function of mitochondrial electron transport chain, was measured densitometrically. The central and peripheral portions of the placenta were studied with respect to their morphological differences. The study has shown that changes in the morphometric parameters of terminal villi and in succinate dehydrogenase (SDH) activity tend to follow a stable 12-hour rhythm with morning and evening maxima. We observed phasic differences in SDH activity and the height of syncytiotrophoblast between central and peripheral terminal villi, which indicates the existence of an intrinsic mechanism integrating the function of the placenta. It seems that the circadian fluctuations in the structure and activity of the placenta and consequent fluctuations in substrate exchange between the mother and children could be an important consideration in clinical practice.
Keywords: Circadian Rhythm, Placenta, morphometry, syncytiotrophoblast, Succinate Dehydrogenase
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
21 Mar 2024 : Meta-Analysis
Economic Evaluation of COVID-19 Screening Tests and Surveillance Strategies in Low-Income, Middle-Income, a...Med Sci Monit In Press; DOI: 10.12659/MSM.943863
10 Apr 2024 : Clinical Research
Predicting Acute Cardiovascular Complications in COVID-19: Insights from a Specialized Cardiac Referral Dep...Med Sci Monit In Press; DOI: 10.12659/MSM.942612
06 Mar 2024 : Clinical Research
Enhanced Surgical Outcomes of Popliteal Cyst Excision: A Retrospective Study Comparing Arthroscopic Debride...Med Sci Monit In Press; DOI: 10.12659/MSM.941102
06 Mar 2024 : Clinical Research
Prevalence and Variation of Medical Comorbidities in Oral Surgery Patients: A Retrospective Study at Jazan ...Med Sci Monit In Press; DOI: 10.12659/MSM.943884
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952