Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 August 2007

Epidemiological and clinical analysis of pemphigoid patients in northeastern Poland in 2000–2005

Agnieszka Beata Serwin, Ewa Bokiniec, Marta Piascik, Dominik Masny, Bozena Chodynicka

Med Sci Monit 2007; 13(8): CR360-364 :: ID: 491651

Abstract

Background: Epidemiological studies on pemphigoid, the most frequent group of autoimmune bullous diseases, are rare. The aim was to evaluate the incidence of pemphigoid in the Podlaskie voivodship (northeastern Poland), the prevalence of concomitant diseases and their treatment, and the efficacy and side effects of pemphigoid therapy.
Material/Methods: The study included 23 female and 12 male consecutive in-patients of the Department of Dermatology and Venereology, Medical University of Białystok , between January 2000 and June 2006. Their sociodemographic data, diseases, and treatment before and after pemphigoid onset were analyzed. Diagnosis was confirmed using direct and/or indirect immunological studies.
Results: The annual incidence of pemphigoid was 4.47/million. Sixty percent of the patients lived in rural areas. Their mean age at diagnosis was 68.99 years in women and 67.25 years in men; five female patients were under 53 years. All patients were treated for other diseases prior to pemphigoid onset and the diseases could have been drug-induced in >30% of cases. Two patients had malignancies prior to pemphigoid onset, and neoplasmas were diagnosed afterwards in three. Prednisolone was a successful treatment in >60% of patients. Infections and osteoporosis were observed in 34.3% during therapy; one patient had sudden gastric hemorrhage. Seven patients died within the first year.
Conclusions: The results confirm that pemphigoid affects mainly elderly people, usually being treated for other disorders; the disease may be more frequent in rural areas. In an aging society, the disease is expected to become a more serious therapeutic challenge.

Keywords: Aged, 80 and over, Autoantigens - chemistry, Autoimmune Diseases - complications, Cardiovascular Diseases - complications, Dermatology - methods, Pemphigoid, Bullous - therapy, Poland, Time Factors

Add Comment 0 Comments

Editorial

01 March 2024 : Editorial  

Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-Thalassemia

Dinah V. Parums

DOI: 10.12659/MSM.944204

Med Sci Monit 2024; 30:e944204

0:00

In Press

18 Mar 2024 : Clinical Research  

Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative Study

Med Sci Monit In Press; DOI: 10.12659/MSM.944136  

0:00

21 Feb 2024 : Clinical Research  

Potential Value of HSP90α in Prognosis of Triple-Negative Breast Cancer

Med Sci Monit In Press; DOI: 10.12659/MSM.943049  

22 Feb 2024 : Review article  

Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943168  

23 Feb 2024 : Clinical Research  

A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943732  

Most Viewed Current Articles

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750