31 May 2007
Cytogenetic Results of Recurrent Spontaneous Abortions in Turkey
Huseyin Yuce, Ibrahim Tekedereli, Halit ElyasMed Sci Monit 2007; 13(6): CR286-289 :: ID: 484142
Abstract
Background: Recurrent spontaneous abortion is defined as at least three consecutive pregnancy losses, occuring in 10% of all pregnancies. In the etiology of recurrent spontaneous abortion, a wide variety of abnormalities, such as anatomic, endocrinologic, and genetic abnormalities, has been reported. The aim of this study was to compare karyotyping results of couples with recurrent spontaneous abortions. This may contribute to elucidating the genetic basis of this condition and warn physicians of the cytogenetic abnormalities in cases with recurrent spontaneous abortions.
Material/Methods: The cytogenetic results of patients with at least two abortions referred to Firat (Euphrates) University, College of Medicine, Department of Medical Biology and Genetics in the six-year period between 2000–2005 were reviewed retrospectively.
Results: Of a total of 421 couples (842 patients), 23 men (2.73%) and 8 women (0.95%) had abnormal karyotypes. Balanced and unbalanced karyotypes and polymorphisms had rates of 1.06%, 0.71%, and 1.9%, respectively, the total rate being 3.68%.
Conclusions: These data show that cytogenetic evaluation is necessary for an accurate approach to elucidating the causes of recurrent spontaneous abortion, and physicians should also be careful of the diversity of chromosomal abnormalities that play important roles in the etiology of recurrent spontaneous abortion.
Keywords: Abortion, Habitual - pathology, Turkey, Pregnancy, Karyotyping, Chromosomes, Human - genetics, Chromosomes, Human - genetics, Turkey, Pregnancy, Karyotyping, Abortion, Habitual - pathology
Editorial
01 May 2022 : Editorial
Editorial: Cardiovascular Complications at One Year After SARS-CoV-2 Infection are Independent of Underlying Cardiovascular Risk Factors or Severity of COVID-19DOI: 10.12659/MSM.937048
Med Sci Monit 2022; 28:e937048
SARS-CoV-2/COVID-19
24 May 2022 : Clinical Research
Screening for SARS-CoV-2 Infection in Students at the Medical University of Warsaw, Poland Between November...Med Sci Monit In Press; DOI: 10.12659/MSM.936962
04 May 2022 : Clinical Research
Effects of Wearing Face Masks on Exercise Capacity and Ventilatory Anaerobic Threshold in Healthy Subjects ...Med Sci Monit In Press; DOI: 10.12659/MSM.936069
22 April 2022 : Clinical Research
Factors Associated with Falls During Hospitalization for Coronavirus Disease 2019 (COVID-19)Med Sci Monit In Press; DOI: 10.12659/MSM.936547
25 May 2022 : Meta-Analysis
Effect of the COVID-19 Pandemic on Serum Vitamin D Levels in People Under Age 18 Years: A Systematic Review...Med Sci Monit 2022; 28:e935823
In Press
25 May 2022 : Review article
Narrative Review of the Mechanism of Hip Prosthesis Dislocation and Methods to Reduce the Risk of DislocationMed Sci Monit In Press; DOI: 10.12659/MSM.935665
24 May 2022 : Clinical Research
Remimazolam Tosilate Sedation with Adjuvant Sufentanil in Chinese Patients with Liver Cirrhosis Undergoing ...Med Sci Monit In Press; DOI: 10.12659/MSM.936580
24 May 2022 : Clinical Research
Screening for SARS-CoV-2 Infection in Students at the Medical University of Warsaw, Poland Between November...Med Sci Monit In Press; DOI: 10.12659/MSM.936962
23 May 2022 : Clinical Research
Fully Automatic Knee Joint Segmentation and Quantitative Analysis for Osteoarthritis from Magnetic Resonanc...Med Sci Monit In Press; DOI: 10.12659/MSM.936733
Most Viewed Current Articles
30 Dec 2021 : Clinical Research
Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...DOI :10.12659/MSM.935379
Med Sci Monit 2021; 27:e935379
08 Mar 2022 : Review article
A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...DOI :10.12659/MSM.936292
Med Sci Monit 2022; 28:e936292
01 Nov 2020 : Review article
Long-Term Respiratory and Neurological Sequelae of COVID-19DOI :10.12659/MSM.928996
Med Sci Monit 2020; 26:e928996
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952