Diagnostic performance of CT colonography in a population with a high prevalence of large bowel disease
Basim M.H. Sallam, Joanna Pilch-Kowalczyk, Katarzyna Gruszczynska, Jan Baron, Francesca Pugliese
Med Sci Monit 2007; 13(1): 105-110
Background: Although CT colonography (CTC) is a well-known diagnostic modality, it is not yet established as an official screening method mainly due to discrepancies in diagnostic accuracy values reported in the literature. We examined the diagnostic accuracy of CTC in a population with suspicion of large bowel disease. Material and Methods: CTC was performed in 77 patients with 2- and 16-slice CT units after the standard preparation. The results were compared with optical colonoscopy (39%) and/or barium enema (35%) and pathomorphological examinations (44%) and statistically evaluated.
Results: CTC visualized large bowel pathology in 75% of patients. Its diagnostic accuracy vs. optical colonoscopy was significant (C=0.8719, p
Keywords: Colonic Polyps - radiography, Colitis, Ulcerative - radiography, Colonography, Computed Tomographic, Colorectal Neoplasms - radiography, Female, Humans, Image Processing, Computer-Assisted, Intestine, Large - radiography, Male, Middle Aged, Reproducibility of Results, Retrospective Studies, Sensitivity and Specificity