01 September 2006
Organic colonic lesions in patients with Irritable Bowel Syndrome (IBS)
Abbasi J. Akhtar, Magda A. Shaheen, Junli ZhaMed Sci Monit 2006; 12(9): CR363-367 :: ID: 455236
Abstract
Background:To determine whether IBS patients develop organic lesions compared to those without IBS, and to determine type and frequency of these organic colonic lesions.
Material/Methods: Retrospective review of medical records of 622 IBS patients, ages 19-91 years, over fifteen years that underwent colonoscopy for new gastrointestinal symptoms during the course of their illness. Records of 642 non-IBS patients, who had colonoscopy for gastrointestinal complaints, were reviewed retrospectively as a comparison group. We abstracted and analyzed data related to demographics, history, diagnosis of IBS, and type of colonic lesions reported in the colonoscopy reports.
Results: Of the 622 patients diagnosed with IBS, the median duration of the IBS was 11 years (range =1 to 62 years). Colonoscopy findings were normal in 301 patients (48.4%) in the IBS group and 301 patients (46.9%) in the non-IBS group. Among the IBS group, the common organic colonic lesions were hemorrhoids (21.1%) polyps (20.3%) and diverticuli (19%) and angiodysplasia (11.9%). Among the non-IBS group, the common organic colonic lesions were hemorrhoids (22.6%), polyps (22.4%), diverticuli (20.6%) and angiodysplasia (12.1%). There was no difference in the prevalence of organic colonic lesions among patients with or without IBS (p>0.05). Adjusting for the demographic variables and the number of lesions, there were no differences between the groups (p>0.05).
Conclusions:IBS patients may also develop organic colonic lesions, thus colonoscopy, if indicated, should not be delayed in these patients because of the assumption that their symptoms are due to IBS alone.
Keywords: Aged, 80 and over, Colon - pathology, Colonic Diseases - epidemiology, Colonoscopy, Irritable Bowel Syndrome - surgery, Prevalence
Editorial
01 March 2024 : Editorial
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-ThalassemiaDOI: 10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
In Press
18 Mar 2024 : Clinical Research
Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative StudyMed Sci Monit In Press; DOI: 10.12659/MSM.944136
21 Feb 2024 : Clinical Research
Potential Value of HSP90α in Prognosis of Triple-Negative Breast CancerMed Sci Monit In Press; DOI: 10.12659/MSM.943049
22 Feb 2024 : Review article
Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...Med Sci Monit In Press; DOI: 10.12659/MSM.943168
23 Feb 2024 : Clinical Research
A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...Med Sci Monit In Press; DOI: 10.12659/MSM.943732
Most Viewed Current Articles
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952