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01 July 2006

Typical Pulmonary Carcinoid Tumors: Presentation and Outcome of 24 Cases

Sinem Gungor, Ebru Damadoglu, Aysun Aybatli, Adnan Yilmaz, Altan Kir, Esen Akkaya

Med Sci Monit 2006; 12(7): CR315-318 :: ID: 452205

Abstract

Background: The aim of the study was to determine the presenting clinical-radiologicalfeatures and outcomes of typical pulmonary carcinoid tumors in our center. Material/Methods: The medicalrecords of 24 patients with typical pulmonary carcinoid tumor diagnosed between January 1995 and December2003 were retrospectively reviewed. Follow-up information on patients was obtained from direct patientcontact in February 2004. Results: There were 17 female and 7 male patients with a mean age of 40.3 years(range: 17-69 years). Sixteen patients (66.7%) were nonsmokers. The most frequent presenting symptomwas cough, followed by hemoptysis. Twenty-three patients had an abnormal chest X-ray, showing atelectasisin seven. Bronchoscopy revealed mass lesion in all cases. In 13 cases, tumor was located in the lobarbronchi. Diagnosis of carcinoid tumor was established with bronchoscopy in 19 patients and with thoracotomyin five cases. While surgery was the treatment modality in 23 patients, one patient refused treatment.Lobectomy was performed in 15 cases and six of them were sleeve lobectomy. One patient died two daysafter operation due to ischemic heart disease, two were lost to follow-up, and 21 patients were stillalive. Survival for the 21 patients was between 5 and 96 months. Eight patients had survival of morethan five years. Conclusions: Our data suggest that typical pulmonary carcinoids are different from majorlung cancer types with respect to sex, age predilection, and smoking history. Surgery is the treatmentof choice for pulmonary carcinoid tumors. These patients had excellent prognosis after surgical treatment.

Keywords: Adolescent, Carcinoid Tumor - radiography, Lung Neoplasms - radiography

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750