Logo MSM

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo MSM Logo MSM Logo MSM

31 December 1969

Serum myoglobin as a marker of skeletal muscle damage from extracorporeal shockwave lithotripsy (ESWL)

Aleksandra Kochańska-Dziurowicz, Andrzej Prajsner, Wojciech Szewczyk, Marzena Jaworska-Kik

Med Sci Monit 1998; 4(6): CR951-954 :: ID: 451730

Abstract

Extracorporeal shock wave lithotripsy (ESWL) is an effective method to treat kidney stones. The soft tissues surrounding the kidney may be damaged as the shock wave passes through on its way to the stone. We measured serum myoglobin concentration to assess skeletal muscle damage as a side effect of ESWL in patients treated for stones in a solitary kidney using shock waves generated at 19 kV with two different total impulse counts - 4000 or 2000 -applied in one session. Sixty-six patients, aged 35-65, were studied. Twenty four patients were excluded with signs of urinary tract infections. Patients were randomly assigned to either 2000 or 4000 impulse count treatment groups. Serum myoglobin concentration was measured by RIA. In the 4000 impulse treatment group, mean serum myoglobin was 75.2±29.8 ng/ml before ESWL, was 82.2±33.7 ng/ml(9.3% increase from baseline) on day 1 after ESWL, and was 93.0±44.9 ng/ml (23.7% increase from baseline) on day 3 after ESWL. In the 2000 impulse treatment group, mean serum myoglobin was 86.6±27.2 ng/ml before ESWL, was 96.2±41.2 ng/ml (11.1% increase from baseline) on day 1 after ESWL, and was 78.9±36.9 ng/ml (8.9% decrease from baseline) on day 3 after ESWL. Changes within and between treatment groups were not statistically significant (p>0.05). These small increases in serum myoglobin concentration after ESWL may indicate skeletal muscle damage. Greater and more persistent increases in serum myoglobin seen after a greater number of impulses applied may indicate more muscle damage. Normalization of serum myoglobin concentration indicates that this damage is transient and ESWL produced no evidence of permanent skeletal muscle damage at the doses used. Moreover, we found no statistical difference in serum myoglobin concentration within groups or between groups.

Keywords: kidney stones, treatment, extracorporeal shock wave lithotripsy (ESWL), complications

0 Comments

Weekly Editorial

27 September 2021 : Editorial

Editorial: Global Regulatory Initiatives Deliver Accelerated Approval of the First Bispecific Therapeutic Monoclonal Antibody for Advanced Non-Small Cell Lung Cancer (NSCLC)

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.934854

Med Sci Monit 2021; 27:e934854

SARS-CoV-2/COVID-19

08 September 2021 : Clinical Research

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

Med Sci Monit In Press; DOI: 10.12659/MSM.932788  

16 July 2021 : Review article

Silent Hypoxemia in Patients with COVID-19 Pneumonia: A Review

Med Sci Monit In Press; DOI: 10.12659/MSM.930776  

09 July 2021 : Database Analysis

A Simple Clinical Prediction Tool for COVID-19 in Primary Care with Epidemiology: Temperature-Leukocytes-CT...

Med Sci Monit In Press; DOI: 10.12659/MSM.931467  

In Press

27 Sep 2021 : Clinical Research

Effect of Combined Thoracic Paravertebral Block and General Anesthesia vs General Anesthesia Alone on Posto...

Med Sci Monit In Press; DOI: 10.12659/MSM.933623  

24 Sep 2021 : Clinical Research

A Single-Center Study of a Resin Inlay Dental Implant-Fixed Prosthesis for Closing Proximal Contact Loss in...

Med Sci Monit In Press; DOI: 10.12659/MSM.933809  

24 Sep 2021 : Database Analysis

Relationships Between Obstructive Sleep Apnea and Cardiovascular Disease: A Bibliometric Analysis (2010-2021)

Med Sci Monit In Press; DOI: 10.12659/MSM.933448  

24 Sep 2021 : Database Analysis

A Statistical Prediction Model for Survival After Kidney Transplantation from Deceased Donors

Med Sci Monit In Press; DOI: 10.12659/MSM.933559  

Most Viewed Current Articles

20 Mar 2020 : Clinical Research

Social Capital and Sleep Quality in Individuals Who Self-Isolated for 14 Days During the Coronavirus Diseas...

DOI :10.12659/MSM.923921

Med Sci Monit 2020; 26:e923921

15 Apr 2020 : Clinical Research

Psychological Impact and Coping Strategies of Frontline Medical Staff in Hunan Between January and March 20...

DOI :10.12659/MSM.924171

Med Sci Monit 2020; 26:e924171

05 May 2020 : Review article

An Evidence Based Perspective on mRNA-SARS-CoV-2 Vaccine Development

DOI :10.12659/MSM.924700

Med Sci Monit 2020; 26:e924700

26 Apr 2020 : Clinical Research

Comparison of Prevalence and Associated Factors of Anxiety and Depression Among People Affected by versus P...

DOI :10.12659/MSM.924609

Med Sci Monit 2020; 26:e924609

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750