01 February 2006
Med Sci Monit 2006; 12(2): RA34-39 :: ID: 445258
Coronary heart disease (CHD) remains the leading cause of mortality inthe United States, and is associated with significant health care costs. Current evidence overwhelminglyconfirms the role of low-density lipoprotein cholesterol (LDL-C) in the pathogenesis of atherosclerosisand the risk of CHD events. The approach to the management of hyperlipidemia has evolved dramaticallyover the past decade. Randomized clinical trails have provided strong evidence that lowering plasma cholesterolwith statins reduces the risk of cardiovascular events, particularly in high-risk patients, irrespectiveof baseline cholesterol levels. The National Cholesterol Education Program (NCEP) report was releasedin July 2004. The report examined the results of recently concluded clinical trials and provided consensusrecommendations on the management of hyperlipidemia. The report expands on the core content of the previouslypublished guidelines. However, it is by far the most aggressive approach to date for reducing CHD risk.A focal element of the report is the modification of LDL-C goal in high-risk patients to
Keywords: Cholesterol, LDL - blood, Cardiovascular Diseases - prevention & control, Azetidines - administration & dosage, Cholestyramine Resin - administration & dosage, Clofibric Acid - administration & dosage, Drug Therapy, Combination, Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use, Hyperlipidemias - therapy, Hypolipidemic Agents - therapeutic use, Life Style, Niacin - administration & dosage, Risk Factors
01 May 2022 : EditorialEditorial: Cardiovascular Complications at One Year After SARS-CoV-2 Infection are Independent of Underlying Cardiovascular Risk Factors or Severity of COVID-19
Med Sci Monit 2022; 28:e937048
04 May 2022 : Clinical ResearchEffects of Wearing Face Masks on Exercise Capacity and Ventilatory Anaerobic Threshold in Healthy Subjects ...
Med Sci Monit In Press; DOI: 10.12659/MSM.936069
22 April 2022 : Clinical ResearchFactors Associated with Falls During Hospitalization for Coronavirus Disease 2019 (COVID-19)
Med Sci Monit In Press; DOI: 10.12659/MSM.936547
17 May 2022 : Clinical ResearchClinical Application of C-TIRADS Category and Contrast-Enhanced Ultrasound in Differential Diagnosis of Sol...
Med Sci Monit In Press; DOI: 10.12659/MSM.936368
17 May 2022 : Laboratory ResearchArtificial Dermal Scaffold Loaded with Platelet-Rich Plasma Promotes Wound Healing in Pigs by Favoring Angi...
Med Sci Monit In Press; DOI: 10.12659/MSM.936186
16 May 2022 : Clinical ResearchEarly Enteral Nutrition Can Reduce Incidence of Postoperative Hydrocephalus in Patients with Severe Hyperte...
Med Sci Monit In Press; DOI: 10.12659/MSM.935850
Most Viewed Current Articles
30 Dec 2021 : Clinical ResearchRetrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...
Med Sci Monit 2021; 27:e935379
08 Mar 2022 : Review articleA Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...
Med Sci Monit 2022; 28:e936292
01 Nov 2020 : Review articleLong-Term Respiratory and Neurological Sequelae of COVID-19
Med Sci Monit 2020; 26:e928996