Risk factors of cardiovascular disease in GH-deficient adults with hypopituitarism: A preliminary report.
Anna Bohdanowicz-Pawlak, Jadwiga Szymczak, Joanna Bladowska, Grażyna Bednarek-Tupikowska, Bożena Bidzińska, Andrzej Milewicz
Med Sci Monit 2006; 12(2): CR75-80
Background: We estimated the influence of GH deficiency (GHD) in adultson chosen risk factors of cardiovascular disease and bone density. Material/Methods: Fifty-four adults(mean age: 50.4 years) with hypopituitarism were studied. We measured blood pressure, body mass index,waist-to-hip ratio, total body fat, and bone mineral density and the serum levels of lipids, glucose,insulin, pituitary hormones, estradiol, testosteron, and thyroxine, and the excretion of free cortisolin 24-h urine. GHD was confirmed with the insulin intravenous test (IIT) with a GH response to IIT of
Keywords: Aged, Adult, Cardiovascular Diseases - etiology, Case-Control Studies, Female, Human Growth Hormone - deficiency, Humans, Hypertension - etiology, Hypopituitarism - diagnosis, Insulin - diagnostic use, Lipids - blood, Male, Middle Aged, Obesity - complications, Risk Factors