01 November 2005
Effect of inhaled salbutamol on dynamic intrinsic positive end-expiratory pressure in spontaneously breathing patients with stable severe chronic obstructive pulmonary diseaseCarlos Alberto Nigro, Jorge Ernesto Prieto, María Mercedes Kleinert, Edgardo Edmundo Rhodius
Med Sci Monit 2005; 11(11): PI81-85 :: ID: 430400
Background: The objective was to determine the effect of inhaled salbutamolon PEEPi dyn in spontaneously breathing patients with stable severe chronic obstructive pulmonary disease(COPD). Material/Methods: Eleven patients with COPD were studied (mean age: 63 years, average FEV(1)0.71+/-0.31 L). The patients were evaluated before and after inhaling 400 g of salbutamol. Spirometry,slow vital capacity, breathing pattern, and PEEPi dyn pre- and post-bronchodilator administration wereperformed. PEEPi dyn was measured as the difference in esophageal pressure between the onset of inspiratoryeffort and the point of zero flow. Results: Pre-BD PEEPi dyn fell on average by 56% after inhalationof salbutamol (1.89+/-1.24 cm H(2)O to 0.83+/-0.81 cm H(2)O, p
Keywords: Administration, Inhalation, Albuterol - administration & dosage, Bronchodilator Agents - administration & dosage, Positive-Pressure Respiration, Pulmonary Disease, Chronic Obstructive - drug therapy, Respiration - drug effects
01 December 2021 : EditorialEditorial: Cardiovascular Complications at One Year After SARS-CoV-2 Infection are Independent of Underlying Cardiovascular Risk Factors or Severity of COVID-19
Med Sci Monit 2022; 28:e937048
04 May 2022 : Clinical ResearchEffects of Wearing Face Masks on Exercise Capacity and Ventilatory Anaerobic Threshold in Healthy Subjects ...
Med Sci Monit In Press; DOI: 10.12659/MSM.936069
22 April 2022 : Clinical ResearchFactors Associated with Falls During Hospitalization for Coronavirus Disease 2019 (COVID-19)
Med Sci Monit In Press; DOI: 10.12659/MSM.936547
27 April 2022 : Meta-AnalysisEffect of the COVID-19 Pandemic on Serum Vitamin D Levels in People Under Age 18 Years: A Systematic Review...
Med Sci Monit In Press; DOI: 10.12659/MSM.935823
20 May 2022 : Clinical ResearchEfficacy of Focused Extracorporeal Shock Wave Therapy in Chronic Low Back Pain: A Prospective Randomized 3-...
Med Sci Monit In Press; DOI: 10.12659/MSM.936614
19 May 2022 : Clinical ResearchAssociation Between Serum Homocysteine Levels and Severity of Diabetic Kidney Disease in 489 Patients with ...
Med Sci Monit In Press; DOI: 10.12659/MSM.936323
18 May 2022 : Clinical ResearchPhysical and Psychosocial Concept Domains Related to Health-Related Quality of Life (HRQL) in 50 Girls and ...
Med Sci Monit In Press; DOI: 10.12659/MSM.936801
Most Viewed Current Articles
31 Dec 1969 : Clinical ResearchRetrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...
Med Sci Monit 2021; 27:e935379
31 Dec 1969 : Review articleA Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...
Med Sci Monit 2022; 28:e936292
31 Dec 1969 : Review articleLong-Term Respiratory and Neurological Sequelae of COVID-19
Med Sci Monit 2020; 26:e928996