Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 November 2005

Clinical Spectrum and Critical Care Management of Posterior Reversible Encephalopathy Syndrome (PRES).

Pasquale Striano, Salvatore Striano, Fabio Tortora, Edoardo De Robertis, Daniela Palumbo, Andrea Elefante, Giuseppe Servillo

Med Sci Monit 2005; 11(11): CR549-553 :: ID: 430371

Abstract

Background: Posterior Reversible Encephalopathy (PRES) is characterizedby acute-onset headache, altered mental status, cortical blindness and seizures, with parietal-occipitalinvolvement. We report all cases of PRES diagnosed in our intensive care unit during the last 4 years,and evaluate their outcome in terms of the different medical treatments used. Even if usually reversible,PRES can sometimes result in death or irreversible neurological deficit, such as chronic epilepsy. Material/Methods:From January 2001 to January 2005, we identified 8 female patients with PRES. All patients underwentbasal and follow-up brain MRI. Patients referred to Epilepsy Center (about 3000 patients) were reviewedin order to identify subjects with a clinical history of PRES. These latter were clinically re-evaluatedand underwent video-EEG, MRI study and neuropsychological testing. Results: Of the 8 patients, 5 hadhypertensive encephalopathy during pregnancy; 2 had eclampsia during the postpartum period; 1 patientwith chronic renal failure developed symptoms after immunosuppressive treatment. In all patients but1, neurological and radiological abnormalities resolved after appropriate treatment. In addition, wefound 2 patients with temporal lobe epilepsy subsequent to a previous PRES. MRI revealed cortical-subcorticalmalacia in the parietal-occipital regions. Conclusions: The widespread use of MRI technology has madePRES familiar to many clinicians. Although PRES is reversible when treatment is instituted, delayed diagnosisand therapy can result in chronic neurological sequelae. The relationship between hypertensive encephalopathyand chronic epilepsy needs to be confirmed by longitudinal studies. Normalization of blood pressure andtreatment of seizures deserves particular attention.

Keywords: Brain Diseases - therapy, Brain - pathology, Blindness, Cortical - diagnosis, Electroencephalography, Epilepsy - therapy, Headache - therapy, Hypertensive Encephalopathy - therapy, Intensive Care, Magnetic Resonance Imaging, Mental Disorders - therapy, Seizures - therapy, Syndrome

0 Comments

Editorial

01 November 2021 : Editorial  

Editorial: What Can be Learned from National and International Vaccine Adverse Event Reporting Systems During the COVID-19 Pandemic?

Dinah V. Parums
Scientific Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.935299

Med Sci Monit 2022; 28:e935299

SARS-CoV-2/COVID-19

26 November 2021 : Editorial  

Editorial: SARS-CoV-2 Vaccine Responses and Breakthrough COVID-19

Med Sci Monit In Press; DOI: 10.12659/MSM.935624  

08 November 2021 : Database Analysis  

Virtual Screening and Molecular Docking to Study the Mechanism of Chinese Medicines in the Treatment of Cor...

Med Sci Monit In Press; DOI: 10.12659/MSM.934102  

25 November 2021 : Clinical Research  

Use of Monoclonal Antibodies Therapy for Treatment of Mild to Moderate COVID-19 in 4 Patients with Rheumato...

Med Sci Monit 2021; 27:e934267

In Press

26 Nov 2021 : Clinical Research  

Serum Uric Acid Levels in Relation to Atrial Fibrillation: A Case-Control Study

Med Sci Monit In Press; DOI: 10.12659/MSM.934007  

26 Nov 2021 : Database Analysis  

Network Pharmacology Integrated Molecular Docking Revealed the Mechanism of Jianpi Yiqi Taohua Decoction Ag...

Med Sci Monit In Press; DOI: 10.12659/MSM.933537  

26 Nov 2021 : Editorial  

Editorial: SARS-CoV-2 Vaccine Responses and Breakthrough COVID-19

Med Sci Monit In Press; DOI: 10.12659/MSM.935624  

26 Nov 2021 : Review article  

A Review of Circulating Tumor DNA in the Diagnosis and Monitoring of Esophageal Cancer

Med Sci Monit In Press; DOI: 10.12659/MSM.934106  

Most Viewed Current Articles

20 Mar 2020 : Clinical Research  

Social Capital and Sleep Quality in Individuals Who Self-Isolated for 14 Days During the Coronavirus Diseas...

DOI :10.12659/MSM.923921

Med Sci Monit 2020; 26:e923921

15 Apr 2020 : Clinical Research  

Psychological Impact and Coping Strategies of Frontline Medical Staff in Hunan Between January and March 20...

DOI :10.12659/MSM.924171

Med Sci Monit 2020; 26:e924171

05 May 2020 : Review article  

An Evidence Based Perspective on mRNA-SARS-CoV-2 Vaccine Development

DOI :10.12659/MSM.924700

Med Sci Monit 2020; 26:e924700

26 Apr 2020 : Clinical Research  

Comparison of Prevalence and Associated Factors of Anxiety and Depression Among People Affected by versus P...

DOI :10.12659/MSM.924609

Med Sci Monit 2020; 26:e924609

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750