09 January 2002
Med Sci Monit 2002; 8(1): RA22-26 :: ID: 420975
The paper presents current views concerning childhood autism. The authorspresent the concepts of etiology of this disorder, emphasizing the role of negative psychical stimuliin early childhood and the role of mother's contact with the child. Organic factors, including geneticbackground, developmental abnormalities of the nervous system, teratogenic factors and perinatal traumasare also taken into consideration. The role of metabolic factors and enterohormones, particularly thosebelonging to the secretin group and their effect on the function of the gastrointestinal tract and centralnervous system is emphasized. We discuss signs which may be indicative of first symptoms of autism indifferent age groups. A typical symptom of autism is no development of speech, observed from infancy,taking the form of complete mutism at later stages. It has been emphasized that most pathologic symptomsresult from altered perception of external stimuli, which arouse fear and anxiety. Autistic patientsmay suffer from gastrointestinal tract disturbances such as abdominal pains and diarrhea. Methods usedhitherto in the therapy of childhood autism, mainly by psychologists and psychiatrists, as well as someattempts of pharmacological treatment, are presented. The structure and function of secretin, as wellas its effects on the motor and secretory function of the stomach and the exocrine function of the pancreasare discussed. The role of secretin in diagnostic tests, among others in the diagnosis of gastrinoma,is emphasized. We also present the history of the application of secretin in the therapy of childhoodautism.
Keywords: Autistic Disorder, Child, Child, Preschool, Gastrointestinal Diseases, Secretin
25 October 2021 : EditorialEditorial: The 2021 European Society of Cardiology (ESC) Guidelines on the Real-World Prevention of Atherosclerotic Cardiovascular Disease (ASCVD)
Med Sci Monit 2021; 27:e935172
22 October 2021 : Clinical ResearchA Novel Method for the Production of an Autologous Anti-Inflammatory and Anti-Catabolic Product (Cytorich) ...
Med Sci Monit In Press; DOI: 10.12659/MSM.934365
11 October 2021 : Clinical ResearchClinical Features and Temporal Lung Radiographic Changes in 25 Patients Recovering from COVID-19 Pneumonia:...
Med Sci Monit In Press; DOI: 10.12659/MSM.933381
08 September 2021 : Clinical ResearchAcceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...
Med Sci Monit In Press; DOI: 10.12659/MSM.932788
22 Oct 2021 : Clinical ResearchUlnar Groove Plasty Guided by a 3D Printing Technique for Moderate to Severe Cubital Tunnel Syndrome Caused...
Med Sci Monit In Press; DOI: 10.12659/MSM.933775
22 Oct 2021 : Clinical ResearchTotal Fluoroscopy Time Reduction During Ultrasound- and Fluoroscopy-Guided Percutaneous Transhepatic Biliar...
Med Sci Monit In Press; DOI: 10.12659/MSM.933889
22 Oct 2021 : Clinical ResearchCorrelation Between Severity of Illness and Levels of Free Triiodothyronine, Interleukin-6, and Interleukin...
Med Sci Monit In Press; DOI: 10.12659/MSM.933230
Most Viewed Current Articles
20 Mar 2020 : Clinical ResearchSocial Capital and Sleep Quality in Individuals Who Self-Isolated for 14 Days During the Coronavirus Diseas...
Med Sci Monit 2020; 26:e923921
15 Apr 2020 : Clinical ResearchPsychological Impact and Coping Strategies of Frontline Medical Staff in Hunan Between January and March 20...
Med Sci Monit 2020; 26:e924171
05 May 2020 : Review articleAn Evidence Based Perspective on mRNA-SARS-CoV-2 Vaccine Development
Med Sci Monit 2020; 26:e924700