09 January 2002
An assessment of the effectiveness of magnetic resonance imaging in delayedsequences after administration of Gd-DTPA contrast in the detection of metastatic lesions in the brain.
Urszula Grzesiakowska, Malgorzata TacikowskaMed Sci Monit 2002; 8(1): MT21-24 :: ID: 420960
Abstract
BACKGROUND: Advances in oncology in recent years have made it possibleto undertake radical interventions even in advanced cases. Local treatment, surgical or radiosurgical,is applied ever more frequently in cases of metastases to the brain. This requires accurate determinationof the number and location of metastases by means of imaging techniques. The goal of our research wasto establish whether the use of sequences delayed by 20-30 minutes after gadolinium injection improvesthe number of metastatic lesions detected in the brain by MRI. MATERIAL/METHODS: Twenty-eight patientswere studied, ranging in age from 24 to 72 years, diagnosed with malignant tumors and suspected metastasesto the brain. MRI examinations were performed with a 2T unit in SE T1 immediately after i.v. administrationof a 0.1 mmol/kg dose of gadolinium, and again 20-30 minutes after contrast injection; both sequenceswere done in axial projection in layers identical as in the SE T1 sequence made before gadolinium injection.The focal lesions were counted and classified by size. The number of detected lesions was calculatedin each group, comparing early and late phases after contrast injection. RESULTS: The number of all nodulesfound in the delayed sequences was significantly higher in comparison to the early phase after gadoliniuminjection. CONCLUSIONS: Delayed sequence should be used to supplement basic sequences in the diagnosisof malignant metastases to the brain in selected oncological cases.
Keywords: Brain, Contrast Media, Gadolinium DTPA, Magnetic Resonance Imaging, Sensitivity and Specificity
Editorial
01 March 2024 : Editorial
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-ThalassemiaDOI: 10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
In Press
21 Feb 2024 : Clinical Research
Potential Value of HSP90α in Prognosis of Triple-Negative Breast CancerMed Sci Monit In Press; DOI: 10.12659/MSM.943049
22 Feb 2024 : Review article
Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...Med Sci Monit In Press; DOI: 10.12659/MSM.943168
23 Feb 2024 : Clinical Research
A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...Med Sci Monit In Press; DOI: 10.12659/MSM.943732
26 Feb 2024 : Clinical Research
Predictive Value of Combined HbA1c and Neutrophil-to-Lymphocyte Ratio for Diabetic Peripheral Neuropathy in...Med Sci Monit In Press; DOI: 10.12659/MSM.942509
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952