01 August 2005
Clinical and morphological diagnosis of cardiac AL amyloidosis: a review offindings and difficulties as illustrated in one case.Monika Prochorec-Sobieszek, Ewa Szufladowicz, Włodzimierz Szaroszyk, Teresa Wagner, Marios Loukas
Med Sci Monit 2005; 11(8): CS45-48 :: ID: 202148
Background: Primary amyloid light-chain (AL) amyloidosis results from plasmacell dyscrasia. Fibrillar deposits of monoclonal immunoglobulin light chains are present in various organs,especially in the heart. The patients suffer from fatal cardiac dysfunction. Case Report: We report thecase of a 54-year-old man with symptoms of cardiac arrhythmia which was refractory to conventional treatmentand ablations. At a later stage of his disease, the diagnosis of AL amyloidosis associated with monoclonalgammapathy of uncertain significance was established. Echocardiography, electrocardiography, serum immunofixationstudies, abdominal fat aspirate biopsy, and bone marrow biopsy indirectly confirmed the diagnosis ofcardiac amyloidosis. The patient died. Conclusions: The diagnosis of AL cardiac amyloidosis is difficult,the prognosis always serious, the available therapy limited, and the mortality high.
Keywords: Amyloidosis - ultrasonography, Amyloidosis - ultrasonography, Biopsy, Bone Marrow Cells - pathology, Cardiomyopathies - ultrasonography
01 January 2022 : EditorialEditorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Patients
Med Sci Monit 2022; 28:e935952
11 January 2022 : Clinical ResearchA Remote Questionnaire-Based Study to Compare Alcohol Use in 1030 Final-Year High School Students in Split-...
Med Sci Monit In Press; DOI: 10.12659/MSM.935567
08 November 2021 : Database AnalysisVirtual Screening and Molecular Docking to Study the Mechanism of Chinese Medicines in the Treatment of Cor...
Med Sci Monit In Press; DOI: 10.12659/MSM.934102
31 December 2021 : Clinical ResearchA Prospective Observational Study of 42 Patients with COVID-19 infection and a History of Hepatitis C Virus...
Med Sci Monit 2021; 27:e935075
17 Jan 2022 : Clinical ResearchUnveiling the Differences in Biological Properties of Dental Pulp Stem Cells from Normal and Inflamed Pulp:...
Med Sci Monit In Press; DOI: 10.12659/MSM.934511
14 Jan 2022 : Database AnalysisIdentification of Key Genes Associated with Brain Metastasis from Breast Cancer: A Bioinformatics Analysis
Med Sci Monit In Press; DOI: 10.12659/MSM.935071
13 Jan 2022 : Review articleA Review of Current Clinical Concepts in the Pathophysiology, Etiology, Diagnosis, and Management of Hyperc...
Med Sci Monit In Press; DOI: 10.12659/MSM.935821
Most Viewed Current Articles
30 Dec 2021 : Clinical ResearchRetrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...
Med Sci Monit 2021; 27:e935379
01 Nov 2020 : Review articleLong-Term Respiratory and Neurological Sequelae of COVID-19
Med Sci Monit 2020; 26:e928996
05 Mar 2020 : Clinical ResearchThe Effects of Social Support on Sleep Quality of Medical Staff Treating Patients with Coronavirus Disease ...
Med Sci Monit 2020; 26:e923549