20 May 2003 : Case report
Liver transplantations in adult recipients – experience of one center
M. Pacholczyk, B. Łągiewska, A. Chmura, J. Trzebicki, L. Adadyński, L. Jureczko, G. Szyszko, U.. Ołdakowska, M. Kołacz, T. Cieciura, W. RowińskiMed Sci Monit 2003; 9(2): 31-34 :: ID: 15307
Abstract
Material/Methods: Between July 2000 and March 2003,48 cadaveric liver transplantation were performed in our department. There were various indications for the treatment.The most common indication was viral hepatitis (27%). Other common indication were:ALD (16.6%),cryptogenic cirrhosis (10.4%),PBC (10.4%),AIH (10.4%),acute liver failure due to Wilson ’s disease (8.3%),PSC (6.2%).HCC was diagnosed in 3 patients with HCV cirrhosis (6.2%). In 46 patients primary liver transplantation was performed. In 2 cases late graft failure (1st liver transplanted else- where)was the indication. Urgent transplantation was required in 9 (18.7%)patients. The whole organ was transplant- ed in all but one case (reduced graft). In 45 patients piggy-back technique was used (93.7%).The use of veno-venous by-pass (biopump)was necessary only in one case.Donor iliac by-pass graft was used to reconstitute arterial blood inflow to the graft in 4 cases (infrarenal –2,supratruncal –1,recipient ’s splenic artery –1).Recipient portal vein thrombectomy was performed during transplantation in 2 cases.In all the cases,the graft was rinsed with the recipient ’s blood in the volume of 300 ml before reperfusion.In all cases except one,biliary anastomosis was per- formed by the end-to-end technique with Levin catheter drainage.All the patients received transcutaneous enteral nutrition in the postoperative period.Standard immunosuppressive regimen consisted of: Prograf and steroids. Results:42 patients (87.5%)were discharged home with a well-functioning liver graft.Mean hospitalization time was 36 days.6 patient died in early postoperative period (septicemia –2,CVA –1,Vanco-resistant Cl.difficile –1,cardiac failure –1,irreversible hepatic coma –1).Further 2 patients died 4 and 13 months after transplantation,respectively (home acquired fungal septicemia,metastatic HCC).Survival rate after urgent transplantations was 55.5%and 94.8% after elective procedure.Actual one year graft and patient survival rate is 84.6%.Four patients required early re-oper- ation;3 for bleeding (G.I.–1,spleen rupture –1,diaphragm oozing –1)and one for biloma.Recurrent active HCV hepatitis requiring INF+Ribavirin treatment was observed in 3 recipients.Acute graft rejection was treated with pulses of Methylprednisolone in 7 recipients (14.5%)
Keywords: Liver Transplantation, complications after liver transplantation, acute liver failure
Editorial
01 March 2024 : Editorial
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-ThalassemiaDOI: 10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
In Press
18 Mar 2024 : Clinical Research
Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative StudyMed Sci Monit In Press; DOI: 10.12659/MSM.944136
21 Feb 2024 : Clinical Research
Potential Value of HSP90α in Prognosis of Triple-Negative Breast CancerMed Sci Monit In Press; DOI: 10.12659/MSM.943049
22 Feb 2024 : Review article
Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...Med Sci Monit In Press; DOI: 10.12659/MSM.943168
23 Feb 2024 : Clinical Research
A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...Med Sci Monit In Press; DOI: 10.12659/MSM.943732
Most Viewed Current Articles
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952