Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

09 September 2002

Biological rhythms and behavior – then and now

Otto Appenzeller, Germaine Cornélissen, Franz Halberg, James Wallace, Costa A. Costa

Med Sci Monit 2002; 8(9): SR27-30 :: ID: 13493

Abstract

Background: Living matter has its own ‘biological time’: a set of rhythmic oscillations, paced by genes whose expression varies over regular cycles. The resulting chronomes, or time structures, are usually
studied in living matter. A human chronome is preserved long after death in the structure of tooth enamel. This fossil record can be compared with contemporary enamel thus providing insight into an ancient biological rhythm, and consequently into behavior in pre-historic civilizations.
Material/Methods: Eight adult 3rd molar teeth from human burials in Atacama oases of Northern Chile, dating from AD 400 to 900 and belonging to the pre-Hispanic San Pedro culture, were compared to
20 discarded contemporaneous teeth from Albuquerque, N. M. USA. Two adjacent, 100 µm thick ground sections from each tooth were examined using a stereoscopic dissecting microscope and polarized light. The intervals between consecutive brown striae of Retzius (TBS)
and the width of the enamel were measured. We recorded the number of TBS and the number of Wilson’s bands and calculated a ratio of enamel width/number of TBS for each section. We used ANOVA for statistical analysis and cosinor methodology for chronomics, time structure (chronome) mapping.
Results: The ‘biological week’ in the chronome (time structure) of ancient enamel, gauged by TBS, varied according to a multiseptan (multiple of seven) component faster than did the multiseptan
of contemporaneous teeth (1/2.7 versus 1/4.6 biological weeks).
Conclusions: Until now no human chronome has been isolated from fossilized structures. Our discovery indicates that behavior of ancient populations, such as rest and work spans, can be deduced to
some extent after millennia.

Keywords: Behavior, Biological Clocks, Dental Enamel - cytology, Dental Enamel - growth & development, Dentition, Fossils, Paleontology, Time Factors

0 Comments

Editorial

01 December 2021 : Editorial  

Editorial: SARS-CoV-2 Vaccine Responses and Breakthrough COVID-19

Dinah V. Parums
Scientific Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.935624

Med Sci Monit 2021; 27:e935624

SARS-CoV-2/COVID-19

03 December 2021 : Laboratory Research  

Influenza and Influenza-Like Respiratory Virus Infections in Children During the 2019/20 Influenza Season a...

Med Sci Monit In Press; DOI: 10.12659/MSM.934862  

08 November 2021 : Database Analysis  

Virtual Screening and Molecular Docking to Study the Mechanism of Chinese Medicines in the Treatment of Cor...

Med Sci Monit In Press; DOI: 10.12659/MSM.934102  

01 December 2021 : Editorial  

Editorial: SARS-CoV-2 Vaccine Responses and Breakthrough COVID-19

Med Sci Monit 2021; 27:e935624

In Press

03 Dec 2021 : Clinical Research  

A Retrospective Single-Center Study of 23 Patients to Compare Gait Before and After Total Hip Arthroplasty ...

Med Sci Monit In Press; DOI: 10.12659/MSM.934558  

03 Dec 2021 : Laboratory Research  

Influenza and Influenza-Like Respiratory Virus Infections in Children During the 2019/20 Influenza Season a...

Med Sci Monit In Press; DOI: 10.12659/MSM.934862  

02 Dec 2021 : Clinical Research  

Comparison of Outcomes Following Neuronavigation-Assisted Aspiration and Thrombolysis Using Single and Mult...

Med Sci Monit In Press; DOI: 10.12659/MSM.934935  

02 Dec 2021 : Clinical Research  

Serum Levels of N-Terminal Pro-Brain Natriuretic Peptide in Gestational Hypertension, Mild Preeclampsia, an...

Med Sci Monit In Press; DOI: 10.12659/MSM.934285  

Most Viewed Current Articles

20 Mar 2020 : Clinical Research  

Social Capital and Sleep Quality in Individuals Who Self-Isolated for 14 Days During the Coronavirus Diseas...

DOI :10.12659/MSM.923921

Med Sci Monit 2020; 26:e923921

15 Apr 2020 : Clinical Research  

Psychological Impact and Coping Strategies of Frontline Medical Staff in Hunan Between January and March 20...

DOI :10.12659/MSM.924171

Med Sci Monit 2020; 26:e924171

05 May 2020 : Review article  

An Evidence Based Perspective on mRNA-SARS-CoV-2 Vaccine Development

DOI :10.12659/MSM.924700

Med Sci Monit 2020; 26:e924700

26 Apr 2020 : Clinical Research  

Comparison of Prevalence and Associated Factors of Anxiety and Depression Among People Affected by versus P...

DOI :10.12659/MSM.924609

Med Sci Monit 2020; 26:e924609

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750