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01 March 2004

Reliability of the rapid bedside whole-blood quantitative cardiac troponin T assay in the diagnosis of myocardial injury in patients with acute coronary syndrome

Salam Saadeddin, Mohammed Habbab, Hisham Siddieg, Mahmoud Fayomi, Rofaida Dafterdar

Med Sci Monit 2004; 10(3): MT43-46 :: ID: 11602

Abstract

BACKGROUND: A rapid bedside whole-blood quantitative cTnT assay has recently been developed. We evaluated

MATERIAL/METHODS: Whole-blood cTnT levels were measured in 96 patients with ACS using the Roche Cardiac Reader[sup]®[/sup] rapid bedside assay device, and the results were compared with serum cTnT levels in the same patients measured by the Roche Elecsys[sup]®[/sup] Immunoanalyzer. There were 50 patients with clinical evidence of myocardial injury and 56 without.

RESULTS: From the qualitative point of view (reporting negative or positive tests), the results of the rapid bedside tests were identical to those obtained by the serum immunoanalyzer. From

CONCLUSIONS: The rapid bedside cTnT assay correlates well with immunoanalyzer measurements between

Keywords: Adult, Coronary Arteriosclerosis - diagnosis, Dose-Response Relationship, Drug, Heart Diseases - diagnosis, Heart Injuries - diagnosis, Immunoassay - instrumentation, Immunoassay - methods, Myocardium - metabolism, Reagent Kits, Diagnostic, Reproducibility of Results, Sensitivity and Specificity, Troponin I - blood, Troponin T - blood, Adult, Coronary Artery Disease - diagnosis, Dose-Response Relationship, Drug, Heart Diseases - diagnosis, Heart Injuries - diagnosis, Immunoassay - methods, Myocardium - metabolism, Reagent Kits, Diagnostic, Reproducibility of Results, Sensitivity and Specificity, Troponin I - blood, Troponin T - blood

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