07 May 2022>: Animal Study
Characterization of Inflammatory Factors and T Cell Subpopulations in a Murine Model of Kawasaki Disease Induced by Cell Wall Extracts (CAWS)
Huifang Xu ABG* , Jing Weng BCE , Quan Bao CE , Fengyan Nie D , Yuqiang Jiang E , Cong Xiao FDOI: 10.12659/MSM.936355
Med Sci Monit 2022; 28:e936355
Figure 2 The CAWS-induced murine model of KD with the activation of pro-inflammatory cytokines and the inactivation of anti-inflammatory cytokines. (A) ELISA and (B) RT-qPCR were utilized for quantifying the serum levels of inflammatory cytokines IL-1β, IL-6, IL-10, G-CSF and TNF-α at 4 weeks following rhG-CSF administration in CAWS-induced mice. * p<0.05; *** p<0.001; and **** p<0.0001. GraphPad Prism software (version 8.0.1; Graph Pad; San Diego, CA, USA) was used to create the pictures.