04 January 2022>: Animal Study
Activation of α7 Nicotinic Acetylcholine Receptor by its Selective Agonist Improved Learning and Memory of Amyloid Precursor Protein/Presenilin 1 (APP/PS1) Mice via the Nrf2/HO-1 PathwayKun Cao 12BCEF , Jie Xiang 13CF , Yang-Ting Dong 34BCD , Yi Xu 13CD , Zhi-Zhong Guan 134ADG*
Med Sci Monit 2022; 28:e933978
Figure 6 Western blot for Nrf2/HO-1 in the brains of APP/PS1 mice. (A, C) Nrf2 expression at 6 and 10 months of age. (B, D) HO-1 expression at 6 and 10 months of age. The values presented are means±SD of n=10 mice. * P<0.05 compared to the wild-type (WT) group; # P<0.05 compared to the APP/PS1 group, as determined by analysis of variance (ANOVA), followed by the Tukey HSD test.