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10 October 2021: Animal Study

Pretreatment with Methylene Blue Protects Against Acute Seizure and Oxidative Stress in a Kainic Acid-Induced Status Epilepticus Model

Yong-feng Wang 1E* , Yan Luo 2C* , Gao-lei Hou 1B , Rui-jing He 3C , Hao-yun Zhang 3F , Yan-Li Yi 3D , Ying Zhang 3B , Zhi-qiang Cui 3AG*

DOI: 10.12659/MSM.933469

Med Sci Monit 2021; 27:e933469

Figure 3 Representative kainic acid-induced seizure patterns on electroencephalogram in the present study. (A) Irregular high-amplitude spikes. (B) periodic epileptiform discharges. (C) High-frequency bursting. (D) A combination of periodic epileptiform discharges and high-frequency bursts of short duration. (Prism 8, version 8.3.0).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750