18 October 2021: Lab/In Vitro Research
Salicylate Induced GABAR Internalization by Dopamine D1-Like Receptors Involving Protein Kinase C (PKC) in Spiral Ganglion Neurons
Jiangyuan Qin ABCDEF , Tingjia Wei BCD , Huiying Chen BCD , Xiaoyu Lin BC , Danxue Qin BC , Fangyu Wei BC , Peiqiang Liu BC , Wenhua Ye BC , Jiping Su ADG*DOI: 10.12659/MSM.933278
Med Sci Monit 2021; 27:e933278
Figure 3 Expression of GABARγ2 proteins before and after PKC inhibitor application. (A) The inhibitory effect of SKF on the surface expression of GABARγ2 was partially reversed by Bis I. Quantitative analysis of GABARγ2 total protein expression showed no considerable difference in these groups. (B) The inhibitory effect of SS, SS+SKF on the surface levels of GABARγ2 was partially reversed by SCH and Bis I. GABARγ2 total protein expression showed no significant difference in these groups. Data are presented as mean±SD. All experiments n=4, * P<0.05, vs the control group, # P<0.05, vs the SKF group, & P<0.05 vs the SS group, by one-way ANOVA and Tukey test. Odyssey 3.0.23 (LI-COR, USA) and SPSS 25.0 (USA) were used for the creation of the figures.