Figure 2 A splenic TB lesion with rim-like enhancement. (A) Conventional US demonstrates a hypoechoic lesion with relatively well-defined boundary (arrows); (B–D), CEUS demonstrates that the lesion began to enhance from the margin at 12 s after injection of the SonoVue (B, arrows) and presents rim-like enhancement at 25 s (C, arrows), followed by hypo-enhancement compared with the peripheral splenic parenchyma in the late parenchymal phase (D, arrows).