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04 June 2021: Animal Study

Effects of β-Asarone on Ischemic Stroke in Middle Cerebral Artery Occlusion Rats by an Nrf2-Antioxidant Response Elements (ARE) Pathway-Dependent Mechanism

Huiying Pan 1BC , Yi Xu 2D , Qian Cai 1E , Meiling Wu 1ABD , Mingxing Ding 1AG*

DOI: 10.12659/MSM.931884

Med Sci Monit 2021; 27:e931884

Figure 5 Western blot for detecting Nrf2-ARE pathway- and apoptosis-related protein expression in brain tissues of MCAO rat models. (A) Representative images for western blot results. The expression of Nrf2-ARE pathway-related proteins including (B) Nrf2 (C) NQO1, (D) GCLM, (E) HO-1, (F) GCLC and apoptosis-related proteins including (G) BAX, (H) CASP3, (I) CASP9, and (J) Bcl-2 was quantified according to the western blots. * p<0.01, *** p<0.001, ****p<0.0001.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750