Live Combined B. subtilis and E. faecium Alleviate Liver Inflammation, Improve Intestinal Barrier Function, and Modulate Gut Microbiota in Mice with Non-Alcoholic Fatty Liver Disease

Jie Jiang; Jie Xiong; Jianbo Ni; Congying Chen; Kezhou Wang

doi:10.12659/MSM.931143

05 September 2021: Animal Study

Live Combined and Alleviate Liver Inflammation, Improve Intestinal Barrier Function, and Modulate Gut Microbiota in Mice with Non-Alcoholic Fatty Liver Disease

Jie Jiang ^1BCDE , Jie Xiong ^1ACEFG* , Jianbo Ni ^2CDE , Congying Chen ^2CD , Kezhou Wang ^3C

DOI: 10.12659/MSM.931143

Med Sci Monit 2021; 27:e931143

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Figure 4 LCBE consolidates the intestinal barrier in mice fed a high-fat diet. (A) Histopathology images of intestine tissues (H&E, 200× magnification). (B) LPS levels in the serum. (C, D) Protein expression levels of occludin and Claudin1 in the intestine. The data are expressed as means±SD. * P<0.05, ** P<0.01, *** P<0.001 vs Chow, # P<0.05, ## P<0.01, ### P<0.001 vs HFD.

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Live Combined and Alleviate Liver Inflammation, Improve Intestinal Barrier Function, and Modulate Gut Microbiota in Mice with Non-Alcoholic Fatty Liver Disease

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