19 August 2021: Lab/In Vitro Research
Hyperglycemia Promotes Liver Metastasis of Colorectal Cancer via Upregulation of Integrin αvβ6
Ben Wang 1ABEG , Shanjie Wang 2B , Wenke Wang 3BC , Enyu Liu 1BD , Sen Guo 1EF , Chuanzong Zhao 1CF , Jun Niu 1AD* , Zongli Zhang 1A*DOI: 10.12659/MSM.930921
Med Sci Monit 2021; 27:e930921
Figure 5 High glucose induced colon cancer cells migration and invasion through integrin αvβ6. HT-29 and WiDr cells were transfected with β6 siRNA (si-β6) or negative control (si-NC) for 24 h. Cell migration (A, B) and cells invasion (C, D) ability was measured with Transwell assay. * P<0.05 vs NG. # P<0.05 vs HG.