16 March 2021>: Clinical Research
Associations Between Cytochrome P450 (CYP) Gene Single-Nucleotide Polymorphisms and Second-to-Fourth Digit Ratio in Chinese University Students
Jing Zhang 12ABCDEF , Mengyi Yang 1B , Pengfei Luan 1B , Wei Jia 1B , Qiujun Liu 1B , Zhanbing Ma 1A , Jie Dang 1A , Hong Lu 1A , Qian Ma 1B , Yanfeng Wang 1B , Chunlan Mu 1B , Zhenghao Huo 13AG*DOI: 10.12659/MSM.930591
Med Sci Monit 2021; 27:e930591
Figure 1 Linkage disequilibrium (LD) map of single-nucleotide polymorphisms (SNPs) in genes CYP17A1 and CYP19A1. A good LD was found among rs1004467, rs2486758, and rs17115149 of CYP17A1(rs1004467 – rs2486758: D’=0.9993, r2=0.1153; rs1004467 – rs17115149: D’=0.6885, r2=0.0202; rs2486758 – rs17115149: D’=0.9964, r2=0.0203); and rs2255192, rs4275794, and rs4646 of CYP19A1(rs2255192 – rs4275794: D’=0.9883, r2=0.9728; rs2255192 – rs4646: D’=0.9992, r2=0.0974; rs4275794 – rs4646: D’=0.9992, r2=0.0978). The haplotypes in the blocks were established based on the LD values.