29 April 2021>: Animal Study
miR-1283 Contributes to Endoplasmic Reticulum Stress in the Development of Hypertension Through the Activating Transcription Factor-4 (ATF4)/C/EBP-Homologous Protein (CHOP) Signaling Pathway
Weihao Chen ABC* , Tianhao Liu EF* , Qiuer Liang F* , Xudong Chen BC , Wencong Tao B , Meixia Fang AE* , Ya Xiao AE* , Liguo Chen AEG*DOI: 10.12659/MSM.930552
Med Sci Monit 2021; 27:e930552
Figure 8 The content of vasoactive substances and clotting factors in serum of of activating transcription factor 4 (ATF4) knockout mice induced by high salt. (A–G) nitric oxide (NO), endothelin 1 (ET-1), endothelial protein C receptor (EPCR), thrombin (TM), von Willebrand factor (vWF), tissue plasminogen activator (tPA), and plasminogen activator inhibitor (PAI). WT-NS – wild-type+normal salt group; WT-HS – wild-type+high salt group; KO-NS – ATF4+/−+normal salt group; KO-HS – ATF4+/−+high salt group. * P<0.05.