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28 June 2021: Clinical Research

Transforming Growth Factor Beta 1 and p44/42 Expression in Cardinal Ligament Tissues of Patients with Pelvic Organ Prolapse

Ying Zhao ABCE , Zhijun Xia ADF* , Te Lin BCF , Meiying Qin BC

DOI: 10.12659/MSM.930433

Med Sci Monit 2021; 27:e930433

Figure 6 Immunohistochemical staining for MMP9, TIMP1, and caspase 3 in the cardinal ligament. (A–F) Representative images showing that compared with the control group, the expression of MMP9 and caspase 3 was significantly higher and that of TIMP1 was significantly lower in the POP group. Quantitative analysis (G–I). * P<0.05. Magnification: 200× (A1–F1) and 400× (A2–F2). POP – pelvic organ prolapse; TGF-β1 – transforming growth factor beta 1.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750