28 June 2021>: Clinical Research
Transforming Growth Factor Beta 1 and p44/42 Expression in Cardinal Ligament Tissues of Patients with Pelvic Organ ProlapseYing Zhao ABCE , Zhijun Xia ADF* , Te Lin BCF , Meiying Qin BC
Med Sci Monit 2021; 27:e930433
Figure 3 Immunohistochemical staining for TGF-β1, p44/42, and phospho-p44/42 in the cardinal ligament. (A–F) Representative images showing that the expression of TGF-β1 and phospho-p44/42 in the control group was statistically significantly higher than that in the POP group. In contrast, the difference in p44/42 expression between the groups was not significant. (G–I) Quantitative analysis. *P<0.05; ns non-significant. Magnification: 200× (A1–F1) and 400× (A2–F2). POP – pelvic organ prolapse; TGF-β1 – transforming growth factor beta 1; P-P44/42 – phospho-p44/42.