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11 June 2021: Animal Study

Protective Effects of Bone Marrow Mesenchymal Stem Cells (BMMSCS) Combined with Normothermic Machine Perfusion on Liver Grafts Donated After Circulatory Death via Reducing the Ferroptosis of Hepatocytes

Dong Sun 1BCDEF* , Liu Yang 1BCEF* , Weiping Zheng 23CE , Huan Cao 14BD , Longlong Wu 5DF , Hongli Song 26AG*

DOI: 10.12659/MSM.930258

Med Sci Monit 2021; 27:e930258

Figure 3 Quality of DCD donor livers ameliorated by BMMSCs combined with NMP. (A) Gross appearance of DCD donor livers; (B) Histopathological change of DCD donor livers. I: warm ischemia at 30 min; II: 6 h in the SCS group; III: 6 h in the P group; IV: 6 h in the BP group. BMMSCs – bone marrow mesenchymal stem cells; P – NMP; BP – NMP combined with BMMSCs; NMP – normothermic machine perfusion; SCS – static cold storage.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750