15 May 2021: Database Analysis
H Long Terminal Repeat-Associating 2 (HHLA2) is a Biomarker of Advanced Stage Hepatocellular Carcinoma and Promotes Tumor Cell Development In Vitro
Min Luo 1ABCE , Yao Xiong 2BCE , Yan Lin 1CD , Rong Liang 1CD , Yongqiang Li 1D , Lianying Ge 3ADE*DOI: 10.12659/MSM.930215
Med Sci Monit 2021; 27:e930215
Figure 2 HHLA2 mRNA and protein are significantly upregulated in hepatocellular carcinoma tissues. Hepatocellular carcinoma (HCC) tissue, para-carcinoma tissue, and normal liver tissue were analyzed from patients in our retrospective cohort. (A) HHLA2 mRNA expression was significantly higher in the HCC tissues than in the para-carcinoma tissues and normal liver tissues (both *** P<0.001). (B) Respective cases by western blot showing HHLA2 protein levels in paired samples of HCC tissues (C43–C46), para-carcinoma tissues (P43–P46), and normal liver tissues (N1–N8).