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01 April 2021: Animal Study

Effect of Fluorofenidone Against Paraquat-Induced Pulmonary Fibrosis Based on Metabolomics and Network Pharmacology

Feiya Jiang 1AE , Tongtong Wang 1B , Sha Li 2D , Yu Jiang 3C , Zhuo Chen 4F , Wen Liua 1AG*

DOI: 10.12659/MSM.930166

Med Sci Monit 2021; 27:e930166

Figure 1 Pathological changes in rat lung tissue were observed under a light microscope. (A) Representative images of H&E and Masson’s-stained lung sections from the 4 experimental groups (magnification: 200×); (B) Statistical analysis of the levels of alveolitis and pulmonary fibrosis scores. ** P<0.01 vs the control group; # P<0.05 vs the PQ group. PQ – paraquat; AKF-PD – fluorofenidone.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750