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10 May 2021: Clinical Research

Functional Magnetic Resonance Imaging of Language Following Constraint-Induced Aphasia Therapy Primed with Intermittent Theta Burst Stimulation in 13 Patients with Post-Stroke Aphasia

Jane B. Allendorfer 1BCDEF* , Rodolphe Nenert 1BCDE , Sangeeta Nair 1CDE , Jennifer Vannest 2ABDE , Jerzy P. Szaflarski 13ABCDEFG

DOI: 10.12659/MSM.930100

Med Sci Monit 2021; 27:e930100

Figure 1 Overview of study recruitment and procedures. (A) CONSORT flow diagram outlining recruitment of subjects who suffered a left middle cerebral artery stroke and participated in the magnetic resonance imaging (MRI) study before and after treatment with constraint-induced aphasia therapy (CIAT) primed with intermittent theta burst stimulation (iTBS; modified after Szaflarski et al (2018) [3]). (B) Schematic of the open label study procedures. Participants performed language testing and MRI at baseline within 1 week of treatment initiation (T1), within 1 week of treatment completion (T2), and again after 12 weeks following treatment completion (T3).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750