18 August 2021>: Database Analysis
Genome-Wide Profiling of Alternative Splicing Signatures Associated with Prognosis and Immune Microenvironment of Hepatocellular Carcinoma
Zhikun Liu 12ABCDEF , Jiangwei Ye 13ABCDE , Abid Ali Khan 12ABCDEF , Jun Chen 12BCDE , Lin Zhou 2BCDE , Shusen Zheng 2ADE , Xiao Xu 12ADG*DOI: 10.12659/MSM.930052
Med Sci Monit 2021; 27:e930052
Figure 9 Survival-associated SFs and splicing correlation network in HCC patients. (A) Splicing correlation network. AS events with PSI values negatively/positively associated with survival are shown in red/green dots, respectively. SFs related to survival are presented as purple dots. Green/red lines represent negative/positive between SFs expression and PSI values of AS, respectively. (B) High expression (red line) of splicing factor SRSF2 is strongly related to poor disease-free survival (left panel) and poor overall survival (right panel). (C) Dot plot of correlation between expression of SRSF2 and AP PSI values of CAPRIN1 (left panel), and the correlation between ES PSI values of SULT1A2 and expression of SRSF2 (right panel).