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18 August 2021: Database Analysis

Genome-Wide Profiling of Alternative Splicing Signatures Associated with Prognosis and Immune Microenvironment of Hepatocellular Carcinoma

Zhikun Liu 12ABCDEF , Jiangwei Ye 13ABCDE , Abid Ali Khan 12ABCDEF , Jun Chen 12BCDE , Lin Zhou 2BCDE , Shusen Zheng 2ADE , Xiao Xu 12ADG*

DOI: 10.12659/MSM.930052

Med Sci Monit 2021; 27:e930052

Figure 6 The relationship between AS events and the tumor immune microenvironment. (A) Clustering of HCC microenvironment phenotypes based on the estimated scores of 43 cell subsets. The average score of the cell type was used as indicated by Aran, Bindea, or Charoentong in cases where there were common cell types among the different methods (Aran, Bindea, and Charoentong). (B) Recurrence-free survival analyses for the different immune subtypes; left panel: 3 immune clusters and right panel: cluster1 divided into active (cluster 1A) and exhausted (cluster 1B) subtypes.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750