21 June 2021>: Lab/In Vitro Research
Salvianolic Acid A Protects H9C2 Cardiomyocytes from Doxorubicin-Induced Damage by Inhibiting NFKB1 Expression Thereby Downregulating Long-Noncoding RNA (lncRNA) Plasmacytoma Variant Translocation 1 (PVT1)
Yumeng Wu 1ABF , Wei Xiu 2CD , Yubo Wu 1AEF*DOI: 10.12659/MSM.929824
Med Sci Monit 2021; 27:e929824
Figure 1 The effect of salvianolic acid A (SalA) and doxorubicin (Dox) on H9C2 cell viability. (A) the chemical structure of SalA. (B–D) H9C2 cells were exposed to 0, 2, 10, and 50 μM SalA for 12 h (B); 0, 1, 2, 4, and 8 μM Dox for 12 h (C); or SalA and 4 μM Dox co-treatment for 12 h (D). Cell viability was then measured by CCK-8 assay. *** P<0.001; # P<0.05; ### P<0.001.