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05 June 2021: Animal Study

Anti-Psoriatic Effects of Middle Fragment of Chlamydial Plasmid-Encoded Protein pGP3 in an Imiquimod-Induced Psoriasis Mouse Model

Yiming Zhang 1A* , Miaomiao Ma 2A* , Jun Li 3D , Yingye Wu 2C , Lu Xue 2C , Rongrong Zhao 2B , Lu Wang 2E , Shuping Hou 2G* , Huiping Wang 2G*

DOI: 10.12659/MSM.929781

Med Sci Monit 2021; 27:e929781

Figure 4 PASI scores were used to evaluate the degree of (A) erythema, (B) thickness, and (C) scaling of mouse dorsal skin in the normal, imiquimod (IMQ), phosphate-buffered saline intramuscular injection (IM-PBS), pGP3 intramuscular injection (IM-pGP3), and pGP3M intramuscular injection (IM-pGP3M) groups. PASI was scored on a 0–4-point scale. (D) Cumulative score (erythema score+thickness score+scaling score). * P<0.05 compared with the IM-PBS group.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750