18 April 2021>: Animal Study
Left Ventricular Impaired Relaxation and Interstitial Myocarditis Identified in Sepsis-Associated Cardiac Dysfunction: Use of a Rodent ModelDavid J. Sturgess 1ABCDEFG* , Shannon Morrison 1BCDE , Brian Haluska 2BCD , Glenda C. Gobe 23BCDEG , Mark A. Jones 4ACDE , Sonia Volante 1BE , Bala Venkatesh 2ACDEG
Med Sci Monit 2021; 27:e929512
Figure 1 Heart histopathology and immunohistochemistry (IHC). Panels on left are examples of control hearts and on right are LPS treatments. A and B are hematoxylin and eosin stains showing clear hydropic change in the cells of the LPS treatment. C and D contrast ED1 IHC (monocyte/macrophage) with examples of labeled cells arrowed in D. E and F contrast activated caspase-3 IHC (apoptotic cells) with examples arrowed in F and negligible labeling in E.