20 April 2021>: Clinical Research
Overexpression of circ_0021739 in Peripheral Blood Mononuclear Cells in Women with Postmenopausal Osteoporosis Is Associated with Reduced Expression of microRNA-194-5p in Osteoclasts
Jiaxin Guan 1BCEF , Lu Gan 1B , Di Jin 1ACD , Xiaowei Wu 1B , Luyang Cheng 1C , Meiling Liu 1C , Ying Fan 1B , Jing Zhou 2B , Hanlu Zhang 1B , Yina Zhang 1AFG* , Ping Zhou 1FG*DOI: 10.12659/MSM.929170
Med Sci Monit 2021; 27:e929170
Figure 2 Correlation between hsa_circ_0021739 expression and clinical characteristics of patients with postmenopausal osteoporosis (PMOP). (A–C) Correlation between hsa_circ_0021739 expression and T-scores for the lumbar vertebra, femur, and forearm. (D) Receiver-operating characteristic (ROC) curve for hsa_circ_0021739 expression in peripheral blood mononuclear cells (PBMCs) of PMOP patients (area under the curve [AUC]: 0.849, confidence interval [CI]: 0.724–0.932, P<0.001).